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Mitochondrial DNA sequences and transcriptomic profiles for elucidating the genetic underpinnings of cisplatin responsiveness in oral squamous cell carcinoma

OBJECTIVES: Functional genetic variation plays an important role in predicting patients’ response to chemotherapeutic agents. A growing catalogue of mitochondrial DNA (mtDNA) alterations in various cancers point to their important roles in altering the drug responsiveness and survival of cancer cell...

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Detalles Bibliográficos
Autores principales: Aminuddin, Amnani, Ng, Pei Yuen, Chua, Eng Wee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210765/
https://www.ncbi.nlm.nih.gov/pubmed/35729497
http://dx.doi.org/10.1186/s12863-022-01062-w

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