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Systemic sclerosis and tachycardia–bradycardia syndrome: a case report

BACKGROUND: Systemic sclerosis is a multisystemic character autoimmune disease. It is characterized by vascular dysfunction and progressive fibrosis affecting mainly the skin but also different internal organs. All heart structures are commonly affected, including the pericardium, myocardium, and co...

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Autores principales: Faraj, Raid, Laktib, Nabil, Hilal, Safae, Hassan, Fadoun, Krimech, Amine, Bouanani, Alaa, Sarsari, Mohamed, Fellat, Ibtissam, Zarzur, Jamila, Cherti, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210766/
https://www.ncbi.nlm.nih.gov/pubmed/35729641
http://dx.doi.org/10.1186/s13256-022-03462-z
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author Faraj, Raid
Laktib, Nabil
Hilal, Safae
Hassan, Fadoun
Krimech, Amine
Bouanani, Alaa
Sarsari, Mohamed
Fellat, Ibtissam
Zarzur, Jamila
Cherti, Mohamed
author_facet Faraj, Raid
Laktib, Nabil
Hilal, Safae
Hassan, Fadoun
Krimech, Amine
Bouanani, Alaa
Sarsari, Mohamed
Fellat, Ibtissam
Zarzur, Jamila
Cherti, Mohamed
author_sort Faraj, Raid
collection PubMed
description BACKGROUND: Systemic sclerosis is a multisystemic character autoimmune disease. It is characterized by vascular dysfunction and progressive fibrosis affecting mainly the skin but also different internal organs. All heart structures are commonly affected, including the pericardium, myocardium, and conduction system. However, tachycardia–bradycardia syndrome is not common in the literature as a cardiac complication of systemic sclerosis. Case presentation We report a case of tachycardia–bradycardia syndrome in a 46-year-old Moroccan woman followed for systemic sclerosis with cutaneous, vascular, and articular manifestations. The diagnosis was based mainly on patient-reported symptoms and electrocardiogram data. A permanent pacemaker was implanted, allowing the introduction of beta-blockers with good outcomes. CONCLUSIONS: This case aims to show that even minor electrocardiogram abnormalities should be monitored in this group of patients, preferably by 24-hour ambulatory electrocardiogram because they could be a good indicator of the activity and progression of cardiac fibrosis.
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spelling pubmed-92107662022-06-22 Systemic sclerosis and tachycardia–bradycardia syndrome: a case report Faraj, Raid Laktib, Nabil Hilal, Safae Hassan, Fadoun Krimech, Amine Bouanani, Alaa Sarsari, Mohamed Fellat, Ibtissam Zarzur, Jamila Cherti, Mohamed J Med Case Rep Case Report BACKGROUND: Systemic sclerosis is a multisystemic character autoimmune disease. It is characterized by vascular dysfunction and progressive fibrosis affecting mainly the skin but also different internal organs. All heart structures are commonly affected, including the pericardium, myocardium, and conduction system. However, tachycardia–bradycardia syndrome is not common in the literature as a cardiac complication of systemic sclerosis. Case presentation We report a case of tachycardia–bradycardia syndrome in a 46-year-old Moroccan woman followed for systemic sclerosis with cutaneous, vascular, and articular manifestations. The diagnosis was based mainly on patient-reported symptoms and electrocardiogram data. A permanent pacemaker was implanted, allowing the introduction of beta-blockers with good outcomes. CONCLUSIONS: This case aims to show that even minor electrocardiogram abnormalities should be monitored in this group of patients, preferably by 24-hour ambulatory electrocardiogram because they could be a good indicator of the activity and progression of cardiac fibrosis. BioMed Central 2022-06-21 /pmc/articles/PMC9210766/ /pubmed/35729641 http://dx.doi.org/10.1186/s13256-022-03462-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Faraj, Raid
Laktib, Nabil
Hilal, Safae
Hassan, Fadoun
Krimech, Amine
Bouanani, Alaa
Sarsari, Mohamed
Fellat, Ibtissam
Zarzur, Jamila
Cherti, Mohamed
Systemic sclerosis and tachycardia–bradycardia syndrome: a case report
title Systemic sclerosis and tachycardia–bradycardia syndrome: a case report
title_full Systemic sclerosis and tachycardia–bradycardia syndrome: a case report
title_fullStr Systemic sclerosis and tachycardia–bradycardia syndrome: a case report
title_full_unstemmed Systemic sclerosis and tachycardia–bradycardia syndrome: a case report
title_short Systemic sclerosis and tachycardia–bradycardia syndrome: a case report
title_sort systemic sclerosis and tachycardia–bradycardia syndrome: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210766/
https://www.ncbi.nlm.nih.gov/pubmed/35729641
http://dx.doi.org/10.1186/s13256-022-03462-z
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