Cargando…

Vitamin D Exerts Significant Antitumor Effects by Suppressing Vasculogenic Mimicry in Breast Cancer Cells

BACKGROUND: Numerous clinical and experimental observations have alluded to the substantial anti-neoplastic role of vitamin D in breast cancer (BC), primarily by inducing apoptosis and affecting metastasis. Tumor progression and resistance to chemotherapy have been linked to vasculogenic mimicry (VM...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bajbouj, Khuloud, Al-Ali, Abeer, Shafarin, Jasmin, Sahnoon, Lina, Sawan, Ahmad, Shehada, Ahmed, Elkhalifa, Walaaeldin, Saber-Ayad, Maha, Muhammad, Jibran Sualeh, Elmoselhi, Adel B., Guraya, Salman Y., Hamad, Mawieh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210804/ https://www.ncbi.nlm.nih.gov/pubmed/35747793 http://dx.doi.org/10.3389/fonc.2022.918340

Ejemplares similares

Vitamin D-Mediated Anti-cancer Activity Involves Iron Homeostatic Balance Disruption and Oxidative Stress Induction in Breast Cancer
por: Bajbouj, Khuloud, et al.
Publicado: (2021)

High-Dose Deferoxamine Treatment Disrupts Intracellular Iron Homeostasis, Reduces Growth, and Induces Apoptosis in Metastatic and Nonmetastatic Breast Cancer Cell Lines
por: Bajbouj, Khuloud, et al.
Publicado: (2018)

Estrogen-dependent disruption of intracellular iron metabolism augments the cytotoxic effects of doxorubicin in select breast and ovarian cancer cells
por: Bajbouj, Khuloud, et al.
Publicado: (2019)

Co-targeting BET bromodomain BRD4 and RAC1 suppresses growth, stemness and tumorigenesis by disrupting the c-MYC-G9a-FTH1axis and downregulating HDAC1 in molecular subtypes of breast cancer
por: Ali, Amjad, et al.
Publicado: (2021)

Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells
por: Bajbouj, Khuloud, et al.
Publicado: (2020)

Ferritin heavy chain (FTH1) exerts significant antigrowth effects in breast cancer cells by inhibiting the expression of c‐MYC
por: Ali, Amjad, et al.
Publicado: (2021)

Iron Overload Induces Oxidative Stress, Cell Cycle Arrest and Apoptosis in Chondrocytes
por: Karim, Asima, et al.
Publicado: (2022)

SARS-CoV-2-induced hypomethylation of the ferritin heavy chain (FTH1) gene underlies serum hyperferritinemia in severe COVID-19 patients
por: Muhammad, Jibran Sualeh, et al.
Publicado: (2022)

Luteolin inhibits proliferation, triggers apoptosis and modulates Akt/mTOR and MAP kinase pathways in HeLa cells
por: Raina, Ritu, et al.
Publicado: (2021)

Fisetin Deters Cell Proliferation, Induces Apoptosis, Alleviates Oxidative Stress and Inflammation in Human Cancer Cells, HeLa
por: Afroze, Nazia, et al.
Publicado: (2022)

Carnosic Acid Induces Apoptosis and Inhibits Akt/mTOR Signaling in Human Gastric Cancer Cell Lines
por: El-Huneidi, Waseem, et al.
Publicado: (2021)

Vasculogenic mimicry
por: Pandiar, Deepak, et al.
Publicado: (2023)

BRD4 regulates the induction and maintenance of cancer stem cells in squamous cell carcinoma
por: Hamad, Mawieh, et al.
Publicado: (2022)

Estrogen-induced hypomethylation and overexpression of YAP1 facilitate breast cancer cell growth and survival
por: Muhammad, Jibran Sualeh, et al.
Publicado: (2020)

PRMT5 Selective Inhibitor Enhances Therapeutic Efficacy of Cisplatin in Lung Cancer Cells
por: Bajbouj, Khuloud, et al.
Publicado: (2021)

Histone Modification in NSCLC: Molecular Mechanisms and Therapeutic Targets
por: Bajbouj, Khuloud, et al.
Publicado: (2021)

Advanced research on vasculogenic mimicry in cancer
por: Qiao, Lili, et al.
Publicado: (2015)

Mechanisms of Vasculogenic Mimicry in Ovarian Cancer
por: Ayala-Domínguez, Lízbeth, et al.
Publicado: (2019)

An Overview of Vasculogenic Mimicry in Breast Cancer
por: Andonegui-Elguera, Marco A., et al.
Publicado: (2020)

Vasculogenic mimicry in carcinogenesis and clinical applications
por: Luo, Qingxi, et al.
Publicado: (2020)

Genetic Mutations and Non-Coding RNA-Based Epigenetic Alterations Mediating the Warburg Effect in Colorectal Carcinogenesis
por: Abi Zamer, Batoul, et al.
Publicado: (2021)

MLH1 mediates cytoprotective nucleophagy to resist 5-Fluorouracil-induced cell death in colorectal carcinoma
por: Manzoor, Shaista, et al.
Publicado: (2021)

Clinical significance of vasculogenic mimicry in human gliomas
por: Liu, Xiao-mei, et al.
Publicado: (2011)

Slug promoted vasculogenic mimicry in hepatocellular carcinoma
por: Sun, Dan, et al.
Publicado: (2013)

Vasculogenic mimicry in small cell lung cancer
por: Williamson, Stuart C., et al.
Publicado: (2016)

Structural and functional identification of vasculogenic mimicry in vitro
por: Racordon, Dusan, et al.
Publicado: (2017)

Editorial: Neovascularization, Angiogenesis and Vasculogenic Mimicry in Cancer
por: López-Camarillo, César, et al.
Publicado: (2020)

Platelets disrupt vasculogenic mimicry by cancer cells
por: Martini, Carmela, et al.
Publicado: (2020)

Mechanisms of vasculogenic mimicry in hypoxic tumor microenvironments
por: Wei, Xiaoxu, et al.
Publicado: (2021)

Therapeutic potential of vasculogenic mimicry in urological tumors
por: Lin, Xinyu, et al.
Publicado: (2023)

Advance in vasculogenic mimicry in ovarian cancer (Review)
por: Tian, Xinyuan, et al.
Publicado: (2023)

SARS-CoV-2 Infection-Induced Promoter Hypomethylation as an Epigenetic Modulator of Heat Shock Protein A1L (HSPA1L) Gene
por: Muhammad, Jibran Sualeh, et al.
Publicado: (2021)

Vasculogenic mimicry: a novel target for glioma therapy
por: Chen, Yin-Sheng, et al.
Publicado: (2014)

The relationship between vasculogenic mimicry and epithelial‐mesenchymal transitions
por: Liu, Qiqi, et al.
Publicado: (2016)

Vasculogenic mimicry formation in EBV-associated epithelial malignancies
por: Xiang, Tong, et al.
Publicado: (2018)

Vasculogenic Mimicry: Become an Endothelial Cell “But Not So Much”
por: Fernández-Cortés, Mónica, et al.
Publicado: (2019)

Fact or Fiction, It Is Time for a Verdict on Vasculogenic Mimicry?
por: Valdivia, Andrés, et al.
Publicado: (2019)

Angiogenesis and vasculogenic mimicry as therapeutic targets in ovarian cancer
por: Lim, Dansaem, et al.
Publicado: (2020)

Regulation Networks Driving Vasculogenic Mimicry in Solid Tumors
por: Hernández de la Cruz, Olga N., et al.
Publicado: (2020)

Molecular Mechanisms and Anticancer Therapeutic Strategies in Vasculogenic Mimicry
por: Zhang, Xue, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_l5fm5ccgbhs2k1tdnnrikmvdan