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T405, a New Penem, Exhibits In Vivo Efficacy against M. abscessus and Synergy with β-Lactams Imipenem and Cefditoren

Mycobacteroides abscessus (Mab) is an emerging environmental microbe that causes chronic lung disease in patients with compromised lung function such as cystic fibrosis and bronchiectasis. It is intrinsically resistant to most antibiotics, therefore there are only few antibiotics that can be repurpo...

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Detalles Bibliográficos
Autores principales: Rimal, Binayak, Batchelder, Hunter R., Story-Roller, Elizabeth, Panthi, Chandra M., Tabor, Chavis, Nuermberger, Eric L., Townsend, Craig A., Lamichhane, Gyanu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9211421/
https://www.ncbi.nlm.nih.gov/pubmed/35638855
http://dx.doi.org/10.1128/aac.00536-22

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