Intrinsic function of the peptidylarginine deiminase PADI4 is dispensable for normal haematopoiesis

Peptidylarginine deiminases (PADIs) are strongly associated with the development of autoimmunity, neurodegeneration and cancer but their physiological roles are ill-defined. The nuclear deiminase PADI4 regulates pluripotency in the mammalian pre-implantation embryo but its function in tissue develop...

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Detalles Bibliográficos
Autores principales: Young, Christine, Russell, John R., Van De Lagemaat, Louie N., Lawson, Hannah, Mapperley, Christopher, Kranc, Kamil R., Christophorou, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212077/
https://www.ncbi.nlm.nih.gov/pubmed/35603697
http://dx.doi.org/10.1242/bio.059143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212077/
https://www.ncbi.nlm.nih.gov/pubmed/35603697
http://dx.doi.org/10.1242/bio.059143

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