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Magnetic resonance enterography and bowel ultrasonography in Saudi Arabian patients with Crohn's disease: A correlation study

BACKGROUND: Crohn's disease (CD) is a complex autoimmune disease that results in chronic inflammation of the gastrointestinal tract. CD activity is determined through clinical, laboratory, endoscopic, and radiological evaluations. Studies that examine the data of radiological modalities of eval...

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Autores principales: Ahmad, Rani, Abduljabbar, Ahmed, Wazzan, Mohammad, Thabit, Rawan, Mosli, Mahmoud, Saadah, Omar I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212113/
https://www.ncbi.nlm.nih.gov/pubmed/34380869
http://dx.doi.org/10.4103/sjg.sjg_261_21
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author Ahmad, Rani
Abduljabbar, Ahmed
Wazzan, Mohammad
Thabit, Rawan
Mosli, Mahmoud
Saadah, Omar I.
author_facet Ahmad, Rani
Abduljabbar, Ahmed
Wazzan, Mohammad
Thabit, Rawan
Mosli, Mahmoud
Saadah, Omar I.
author_sort Ahmad, Rani
collection PubMed
description BACKGROUND: Crohn's disease (CD) is a complex autoimmune disease that results in chronic inflammation of the gastrointestinal tract. CD activity is determined through clinical, laboratory, endoscopic, and radiological evaluations. Studies that examine the data of radiological modalities of evaluation are lacking, particularly in Saudi Arabia. This study compares magnetic resonance enterography (MRE) and ultrasonography (US) findings among patients diagnosed with CD, to uncover a possible correlation between these techniques. METHODS: All patients were assessed for disease activity using MRE and US. RESULTS: A total of 376 patients with CD were recruited. The mean age was 14.9 ± 4.3 years (range, 8–27 years), and males constituted 64% (n = 239) of the cohort. Overall, a strong positive correlation was found between US and MRE evaluations of disease activity (r = 0.83, P < 0.001). US activity correlated positively with MRE findings of enlarged lymph nodes (P < 0.001), bowel wall enhancement (P < 0.001), distal jejunal thickness (P < 0.001), and distal ileal thickness (P < 0.001). The mean difference in wall thickness was significant based on gender (P < 0.001), age in proximal jejunal thickness (P < 0.001), and distal ileal thickness (P = 0.011). CONCLUSIONS: MRE and US correlate significantly as imaging techniques for the assessment of CD activity.
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spelling pubmed-92121132022-06-22 Magnetic resonance enterography and bowel ultrasonography in Saudi Arabian patients with Crohn's disease: A correlation study Ahmad, Rani Abduljabbar, Ahmed Wazzan, Mohammad Thabit, Rawan Mosli, Mahmoud Saadah, Omar I. Saudi J Gastroenterol Original Article BACKGROUND: Crohn's disease (CD) is a complex autoimmune disease that results in chronic inflammation of the gastrointestinal tract. CD activity is determined through clinical, laboratory, endoscopic, and radiological evaluations. Studies that examine the data of radiological modalities of evaluation are lacking, particularly in Saudi Arabia. This study compares magnetic resonance enterography (MRE) and ultrasonography (US) findings among patients diagnosed with CD, to uncover a possible correlation between these techniques. METHODS: All patients were assessed for disease activity using MRE and US. RESULTS: A total of 376 patients with CD were recruited. The mean age was 14.9 ± 4.3 years (range, 8–27 years), and males constituted 64% (n = 239) of the cohort. Overall, a strong positive correlation was found between US and MRE evaluations of disease activity (r = 0.83, P < 0.001). US activity correlated positively with MRE findings of enlarged lymph nodes (P < 0.001), bowel wall enhancement (P < 0.001), distal jejunal thickness (P < 0.001), and distal ileal thickness (P < 0.001). The mean difference in wall thickness was significant based on gender (P < 0.001), age in proximal jejunal thickness (P < 0.001), and distal ileal thickness (P = 0.011). CONCLUSIONS: MRE and US correlate significantly as imaging techniques for the assessment of CD activity. Wolters Kluwer - Medknow 2021-08-11 /pmc/articles/PMC9212113/ /pubmed/34380869 http://dx.doi.org/10.4103/sjg.sjg_261_21 Text en Copyright: © 2021 Saudi Journal of Gastroenterology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Ahmad, Rani
Abduljabbar, Ahmed
Wazzan, Mohammad
Thabit, Rawan
Mosli, Mahmoud
Saadah, Omar I.
Magnetic resonance enterography and bowel ultrasonography in Saudi Arabian patients with Crohn's disease: A correlation study
title Magnetic resonance enterography and bowel ultrasonography in Saudi Arabian patients with Crohn's disease: A correlation study
title_full Magnetic resonance enterography and bowel ultrasonography in Saudi Arabian patients with Crohn's disease: A correlation study
title_fullStr Magnetic resonance enterography and bowel ultrasonography in Saudi Arabian patients with Crohn's disease: A correlation study
title_full_unstemmed Magnetic resonance enterography and bowel ultrasonography in Saudi Arabian patients with Crohn's disease: A correlation study
title_short Magnetic resonance enterography and bowel ultrasonography in Saudi Arabian patients with Crohn's disease: A correlation study
title_sort magnetic resonance enterography and bowel ultrasonography in saudi arabian patients with crohn's disease: a correlation study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212113/
https://www.ncbi.nlm.nih.gov/pubmed/34380869
http://dx.doi.org/10.4103/sjg.sjg_261_21
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