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Single cell transcriptomics reveals dysregulated cellular and molecular networks in a fragile X syndrome model
Despite advances in understanding the pathophysiology of Fragile X syndrome (FXS), its molecular basis is still poorly understood. Whole brain tissue expression profiles have proved surprisingly uninformative, therefore we applied single cell RNA sequencing to profile an FMRP deficient mouse model w...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212148/ https://www.ncbi.nlm.nih.gov/pubmed/35675353 http://dx.doi.org/10.1371/journal.pgen.1010221 |