Single cell transcriptomics reveals dysregulated cellular and molecular networks in a fragile X syndrome model

Despite advances in understanding the pathophysiology of Fragile X syndrome (FXS), its molecular basis is still poorly understood. Whole brain tissue expression profiles have proved surprisingly uninformative, therefore we applied single cell RNA sequencing to profile an FMRP deficient mouse model w...

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Detalles Bibliográficos
Autores principales: Donnard, Elisa, Shu, Huan, Garber, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212148/
https://www.ncbi.nlm.nih.gov/pubmed/35675353
http://dx.doi.org/10.1371/journal.pgen.1010221

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