Identification of Arhgef12 and Prkci as genetic modifiers of retinal dysplasia in the Crb1(rd8) mouse model

Mutations in the apicobasal polarity gene CRB1 lead to diverse retinal diseases, such as Leber congenital amaurosis, cone-rod dystrophy, retinitis pigmentosa (with and without Coats-like vasculopathy), foveal retinoschisis, macular dystrophy, and pigmented paravenous chorioretinal atrophy. Limited c...

Descripción completa

Detalles Bibliográficos
Autores principales: Weatherly, Sonia M., Collin, Gayle B., Charette, Jeremy R., Stone, Lisa, Damkham, Nattaya, Hyde, Lillian F., Peterson, James G., Hicks, Wanda, Carter, Gregory W., Naggert, Jürgen K., Krebs, Mark P., Nishina, Patsy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212170/
https://www.ncbi.nlm.nih.gov/pubmed/35675330
http://dx.doi.org/10.1371/journal.pgen.1009798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212170/
https://www.ncbi.nlm.nih.gov/pubmed/35675330
http://dx.doi.org/10.1371/journal.pgen.1009798

Ejemplares similares