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In-Silico targeting of SARS-CoV-2 NSP6 for drug and natural products repurposing
Non-Structural Protein 6 (NSP6) has a protecting role for SARS-CoV-2 replication by inhibiting the expansion of autophagosomes inside the cell. NSP6 is involved in the endoplasmic reticulum stress response by binding to Sigma receptor 1 (SR1). Nevertheless, NSP6 crystal structure is not solved yet....
Autores principales: | Abdelkader, Ahmed, Elzemrany, Amal A., El-Nadi, Mennatullah, Elsabbagh, Sherif A., Shehata, Moustafa A., Eldehna, Wagdy M., El-Hadidi, Mohamed, Ibrahim, Tamer M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212324/ https://www.ncbi.nlm.nih.gov/pubmed/35738174 http://dx.doi.org/10.1016/j.virol.2022.06.008 |
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