Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1

The currently circulating Omicron sub-variants are the SARS-CoV-2 strains with the highest number of known mutations. Herein, we found that human angiotensin-converting enzyme 2 (hACE2) binding affinity to the receptor-binding domains (RBDs) of the four early Omicron sub-variants (BA.1, BA.1.1, BA.2...

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Detalles Bibliográficos
Autores principales: Li, Linjie, Liao, Hanyi, Meng, Yumin, Li, Weiwei, Han, Pengcheng, Liu, Kefang, Wang, Qing, Li, Dedong, Zhang, Yanfang, Wang, Liang, Fan, Zheng, Zhang, Yuqin, Wang, Qiyue, Zhao, Xin, Sun, Yeping, Huang, Niu, Qi, Jianxun, Gao, George Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212699/
https://www.ncbi.nlm.nih.gov/pubmed/35809570
http://dx.doi.org/10.1016/j.cell.2022.06.023

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