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LUNG ULTRASOUND IN NEONATES WITH COVID-19 PNEUMONIA – THE START OF A NEW ERA

OBJECTIVES: Newborns with SARS-CoV-2 infection that developed respiratory symptoms are a special category of patients, due to the fact that irradiating imaging tools are not recommended at their age. Because of their high cellular division rate, the X-ray and computer tomography scans should be avoi...

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Autores principales: Stoicescu, Emil - Robert, Iacob, Daniela, Iacob, Roxana, Cerbu, Simona, Iacob, Emil-Radu, Manolescu, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212719/
http://dx.doi.org/10.1016/j.ultrasmedbio.2022.04.121
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author Stoicescu, Emil - Robert
Iacob, Daniela
Iacob, Roxana
Cerbu, Simona
Iacob, Emil-Radu
Manolescu, Diana
author_facet Stoicescu, Emil - Robert
Iacob, Daniela
Iacob, Roxana
Cerbu, Simona
Iacob, Emil-Radu
Manolescu, Diana
author_sort Stoicescu, Emil - Robert
collection PubMed
description OBJECTIVES: Newborns with SARS-CoV-2 infection that developed respiratory symptoms are a special category of patients, due to the fact that irradiating imaging tools are not recommended at their age. Because of their high cellular division rate, the X-ray and computer tomography scans should be avoided. The aim of this paper is to investigate the relevance of lung ultrasound (LU) in surveillance of neonates with SARS-CoV-2 infection. MATERIALS: In our study we searched PubMed, ScienceDirect and Embase databases based on the following keyword: ‘newborn’, ‘neonate’, ‘COVID-19’, ‘sonography’, ‘lung ultrasound’. The found articles were selected using inclusion and exclusion criteria, such as: lung ultrasound as diagnostic tool, newborns, neonates and <28 days of life as population of interest and COVID-19 pneumonia as pathology criteria. Moreover, we analysed a group of 11 patients with infection who was admitted at ‘Pius Brinzeu’ County Emergency Clinical Hospital at Neonatology Department. RESULTS: From the total of articles, we selected 8 of them, based on the inclusion and exclusion criteria, and we analysed their results. After that, we compared their resulted data with the ultrasound findings from our evaluated newborns. The main changes found using LU include decreasing to disappearing physiological A-lines, rare or confluent B-lines, subpleural consolidations, and pleura abnormalities such as thickening and irregularities. Furthermore, the severity of lung injuries was analysed based on a 12-area score. CONCLUSIONS: Regarding neonates, lung ultrasound is an important tool in the evaluation of lung injuries associated with this infection, being demonstrated in several reviewed studies. Also, this imaging technique come with the benefits of being a repetitive, radiation-free, easy-to-use and reliable procedure for observing the impact and surveillance of COVID-19 on the neonates’ respiratory system. This imaging method was proved useful also in other respiratory diseases and could eventually be an indispensable item in the management and monitoring of newborns with respiratory infections, contouring new horizons in using it.
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spelling pubmed-92127192022-06-22 LUNG ULTRASOUND IN NEONATES WITH COVID-19 PNEUMONIA – THE START OF A NEW ERA Stoicescu, Emil - Robert Iacob, Daniela Iacob, Roxana Cerbu, Simona Iacob, Emil-Radu Manolescu, Diana Ultrasound Med Biol Pp 54 OBJECTIVES: Newborns with SARS-CoV-2 infection that developed respiratory symptoms are a special category of patients, due to the fact that irradiating imaging tools are not recommended at their age. Because of their high cellular division rate, the X-ray and computer tomography scans should be avoided. The aim of this paper is to investigate the relevance of lung ultrasound (LU) in surveillance of neonates with SARS-CoV-2 infection. MATERIALS: In our study we searched PubMed, ScienceDirect and Embase databases based on the following keyword: ‘newborn’, ‘neonate’, ‘COVID-19’, ‘sonography’, ‘lung ultrasound’. The found articles were selected using inclusion and exclusion criteria, such as: lung ultrasound as diagnostic tool, newborns, neonates and <28 days of life as population of interest and COVID-19 pneumonia as pathology criteria. Moreover, we analysed a group of 11 patients with infection who was admitted at ‘Pius Brinzeu’ County Emergency Clinical Hospital at Neonatology Department. RESULTS: From the total of articles, we selected 8 of them, based on the inclusion and exclusion criteria, and we analysed their results. After that, we compared their resulted data with the ultrasound findings from our evaluated newborns. The main changes found using LU include decreasing to disappearing physiological A-lines, rare or confluent B-lines, subpleural consolidations, and pleura abnormalities such as thickening and irregularities. Furthermore, the severity of lung injuries was analysed based on a 12-area score. CONCLUSIONS: Regarding neonates, lung ultrasound is an important tool in the evaluation of lung injuries associated with this infection, being demonstrated in several reviewed studies. Also, this imaging technique come with the benefits of being a repetitive, radiation-free, easy-to-use and reliable procedure for observing the impact and surveillance of COVID-19 on the neonates’ respiratory system. This imaging method was proved useful also in other respiratory diseases and could eventually be an indispensable item in the management and monitoring of newborns with respiratory infections, contouring new horizons in using it. Published by Elsevier Inc. 2022 2022-06-20 /pmc/articles/PMC9212719/ http://dx.doi.org/10.1016/j.ultrasmedbio.2022.04.121 Text en Copyright © 2022 Published by Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Pp 54
Stoicescu, Emil - Robert
Iacob, Daniela
Iacob, Roxana
Cerbu, Simona
Iacob, Emil-Radu
Manolescu, Diana
LUNG ULTRASOUND IN NEONATES WITH COVID-19 PNEUMONIA – THE START OF A NEW ERA
title LUNG ULTRASOUND IN NEONATES WITH COVID-19 PNEUMONIA – THE START OF A NEW ERA
title_full LUNG ULTRASOUND IN NEONATES WITH COVID-19 PNEUMONIA – THE START OF A NEW ERA
title_fullStr LUNG ULTRASOUND IN NEONATES WITH COVID-19 PNEUMONIA – THE START OF A NEW ERA
title_full_unstemmed LUNG ULTRASOUND IN NEONATES WITH COVID-19 PNEUMONIA – THE START OF A NEW ERA
title_short LUNG ULTRASOUND IN NEONATES WITH COVID-19 PNEUMONIA – THE START OF A NEW ERA
title_sort lung ultrasound in neonates with covid-19 pneumonia – the start of a new era
topic Pp 54
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212719/
http://dx.doi.org/10.1016/j.ultrasmedbio.2022.04.121
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