Identification of potent inhibitors of arenavirus and SARS-CoV-2 exoribonucleases by fluorescence polarization assay

Viral exoribonucleases are uncommon in the world of RNA viruses. To date, they have only been identified in the Arenaviridae and the Coronaviridae families. The exoribonucleases of these viruses play a crucial role in the pathogenicity and interplay with host innate immune response. Moreover, corona...

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Detalles Bibliográficos
Autores principales: Hernández, Sergio, Feracci, Mikael, De Jesus, Carolina Trajano, El Kazzi, Priscila, Kaci, Rafik, Garlatti, Laura, Mondielli, Clemence, Bailly, Fabrice, Cotelle, Philippe, Touret, Franck, de Lamballerie, Xavier, Coutard, Bruno, Decroly, Etienne, Canard, Bruno, Ferron, François, Alvarez, Karine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9212739/
https://www.ncbi.nlm.nih.gov/pubmed/35716929
http://dx.doi.org/10.1016/j.antiviral.2022.105364

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