Cargando…

The SARS-CoV-2 protein NSP2 impairs the silencing capacity of the human 4EHP-GIGYF2 complex

There is an urgent need for a molecular understanding of how SARS-CoV-2 influences the machineries of the host cell. Herein, we focused our attention on the capacity of the SARS-CoV-2 protein NSP2 to bind the human 4EHP-GIGYF2 complex, a key factor involved in microRNA-mediated silencing of gene exp...

Descripción completa

Detalles Bibliográficos
Autores principales: Zou, Limei, Moch, Clara, Graille, Marc, Chapat, Clément
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213009/
https://www.ncbi.nlm.nih.gov/pubmed/35756894
http://dx.doi.org/10.1016/j.isci.2022.104646