Cirrhosis and COVID-19: Diffuse venous thrombosis and its clinical implication

A 60-year-old woman with Hepatitis C infection, cirrhosis, recurrent hepatic hydrothorax, and hepatocellular carcinoma was hospitalized with Coronavirus disease-2019 (COVID-19). After her initial discharge, she was re-admitted three weeks later with decompensated liver disease. Imaging revealed exte...

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Autores principales: Canastar, Mehtap, Okumura, Kenji, Bodin, Roxana, Gilet, Anthony, Dhand, Abhay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Masson SAS. 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213027/
https://www.ncbi.nlm.nih.gov/pubmed/38013900
http://dx.doi.org/10.1016/j.liver.2022.100105
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author Canastar, Mehtap
Okumura, Kenji
Bodin, Roxana
Gilet, Anthony
Dhand, Abhay
author_facet Canastar, Mehtap
Okumura, Kenji
Bodin, Roxana
Gilet, Anthony
Dhand, Abhay
author_sort Canastar, Mehtap
collection PubMed
description A 60-year-old woman with Hepatitis C infection, cirrhosis, recurrent hepatic hydrothorax, and hepatocellular carcinoma was hospitalized with Coronavirus disease-2019 (COVID-19). After her initial discharge, she was re-admitted three weeks later with decompensated liver disease. Imaging revealed extensive thrombosis in the portal vein, superior mesenteric vein, splenic vein and bilateral brachial veins. Given the acute onset and extent of the thrombosis, the patient received therapeutic anticoagulation despite elevated prothrombin time/ international normalized ratio, thrombocytopenia and low fibrinogen. Cirrhotic patients with COVID-19 maybe at high risk of thrombosis, which can present with significant hepatic decompensation.
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spelling pubmed-92130272022-06-22 Cirrhosis and COVID-19: Diffuse venous thrombosis and its clinical implication Canastar, Mehtap Okumura, Kenji Bodin, Roxana Gilet, Anthony Dhand, Abhay Journal of Liver Transplantation Case Report A 60-year-old woman with Hepatitis C infection, cirrhosis, recurrent hepatic hydrothorax, and hepatocellular carcinoma was hospitalized with Coronavirus disease-2019 (COVID-19). After her initial discharge, she was re-admitted three weeks later with decompensated liver disease. Imaging revealed extensive thrombosis in the portal vein, superior mesenteric vein, splenic vein and bilateral brachial veins. Given the acute onset and extent of the thrombosis, the patient received therapeutic anticoagulation despite elevated prothrombin time/ international normalized ratio, thrombocytopenia and low fibrinogen. Cirrhotic patients with COVID-19 maybe at high risk of thrombosis, which can present with significant hepatic decompensation. The Author(s). Published by Elsevier Masson SAS. 2022 2022-06-17 /pmc/articles/PMC9213027/ /pubmed/38013900 http://dx.doi.org/10.1016/j.liver.2022.100105 Text en © 2022 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Case Report
Canastar, Mehtap
Okumura, Kenji
Bodin, Roxana
Gilet, Anthony
Dhand, Abhay
Cirrhosis and COVID-19: Diffuse venous thrombosis and its clinical implication
title Cirrhosis and COVID-19: Diffuse venous thrombosis and its clinical implication
title_full Cirrhosis and COVID-19: Diffuse venous thrombosis and its clinical implication
title_fullStr Cirrhosis and COVID-19: Diffuse venous thrombosis and its clinical implication
title_full_unstemmed Cirrhosis and COVID-19: Diffuse venous thrombosis and its clinical implication
title_short Cirrhosis and COVID-19: Diffuse venous thrombosis and its clinical implication
title_sort cirrhosis and covid-19: diffuse venous thrombosis and its clinical implication
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213027/
https://www.ncbi.nlm.nih.gov/pubmed/38013900
http://dx.doi.org/10.1016/j.liver.2022.100105
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