Cargando…

Imlifidase-generated Single-cleaved IgG: Implications for Transplantation

Imlifidase is an immunoglobulin G (IgG)-specific protease conditionally approved in the EU for desensitization in highly sensitized crossmatch positive kidney transplant patients. Imlifidase efficiently cleaves both heavy chains of IgG in a 2-step process. However, low levels of the intermediate cle...

Descripción completa

Detalles Bibliográficos
Autores principales: Bockermann, Robert, Järnum, Sofia, Runström, Anna, Lorant, Tomas, Winstedt, Lena, Palmqvist, Niklas, Kjellman, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213077/
https://www.ncbi.nlm.nih.gov/pubmed/34966107
http://dx.doi.org/10.1097/TP.0000000000004031