Cargando…
Imlifidase-generated Single-cleaved IgG: Implications for Transplantation
Imlifidase is an immunoglobulin G (IgG)-specific protease conditionally approved in the EU for desensitization in highly sensitized crossmatch positive kidney transplant patients. Imlifidase efficiently cleaves both heavy chains of IgG in a 2-step process. However, low levels of the intermediate cle...
Autores principales: | Bockermann, Robert, Järnum, Sofia, Runström, Anna, Lorant, Tomas, Winstedt, Lena, Palmqvist, Niklas, Kjellman, Christian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213077/ https://www.ncbi.nlm.nih.gov/pubmed/34966107 http://dx.doi.org/10.1097/TP.0000000000004031 |
Ejemplares similares
-
Complete Removal of Extracellular IgG Antibodies in a Randomized Dose-Escalation Phase I Study with the Bacterial Enzyme IdeS – A Novel Therapeutic Opportunity
por: Winstedt, Lena, et al.
Publicado: (2015) -
Imlifidase Desensitization in Crossmatch-positive, Highly Sensitized Kidney Transplant Recipients: Results of an International Phase 2 Trial (Highdes)
por: Jordan, Stanley C., et al.
Publicado: (2021) -
Safety, immunogenicity, pharmacokinetics, and efficacy of degradation of anti‐HLA antibodies by IdeS (imlifidase) in chronic kidney disease patients
por: Lorant, Tomas, et al.
Publicado: (2018) -
Outcomes at 3 years posttransplant in imlifidase‐desensitized kidney transplant patients
por: Kjellman, Christian, et al.
Publicado: (2021) -
Streptococcus pyogenes Infection and the Human Proteome with a Special Focus on the Immunoglobulin G-cleaving Enzyme IdeS
por: Karlsson, Christofer A. Q., et al.
Publicado: (2018)