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Current Progress on Neuroprotection Induced by Artemisia, Ginseng, Astragalus, and Ginkgo Traditional Chinese Medicines for the Therapy of Alzheimer's Disease

Aging is associated with the occurrence of diverse degenerative changes in various tissues and organs and with an increased incidence of neurological disorders, especially neurodegenerative diseases such as Alzheimer's disease (AD). In recent years, the search for effective components derived f...

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Detalles Bibliográficos
Autores principales: Li, Qin, Rubin, Limor, Silva, Marta, Li, Shuai, Yang, Chao, Lazarovici, Philip, Zheng, Wenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213169/
https://www.ncbi.nlm.nih.gov/pubmed/35746960
http://dx.doi.org/10.1155/2022/3777021
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author Li, Qin
Rubin, Limor
Silva, Marta
Li, Shuai
Yang, Chao
Lazarovici, Philip
Zheng, Wenhua
author_facet Li, Qin
Rubin, Limor
Silva, Marta
Li, Shuai
Yang, Chao
Lazarovici, Philip
Zheng, Wenhua
author_sort Li, Qin
collection PubMed
description Aging is associated with the occurrence of diverse degenerative changes in various tissues and organs and with an increased incidence of neurological disorders, especially neurodegenerative diseases such as Alzheimer's disease (AD). In recent years, the search for effective components derived from medicinal plants in delaying aging and preventing and treating neurodegenerative diseases has been increasing and the number of related publications shows a rising trend. Here, we present a concise, updated review on the preclinical and clinical research progress in the assessment of the therapeutic potential of different traditional Chinese medicines and derived active ingredients and their effect on the signaling pathways involved in AD neuroprotection. Recognized by their multitargeting ability, these natural compounds hold great potential in developing novel drugs for AD.
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spelling pubmed-92131692022-06-22 Current Progress on Neuroprotection Induced by Artemisia, Ginseng, Astragalus, and Ginkgo Traditional Chinese Medicines for the Therapy of Alzheimer's Disease Li, Qin Rubin, Limor Silva, Marta Li, Shuai Yang, Chao Lazarovici, Philip Zheng, Wenhua Oxid Med Cell Longev Review Article Aging is associated with the occurrence of diverse degenerative changes in various tissues and organs and with an increased incidence of neurological disorders, especially neurodegenerative diseases such as Alzheimer's disease (AD). In recent years, the search for effective components derived from medicinal plants in delaying aging and preventing and treating neurodegenerative diseases has been increasing and the number of related publications shows a rising trend. Here, we present a concise, updated review on the preclinical and clinical research progress in the assessment of the therapeutic potential of different traditional Chinese medicines and derived active ingredients and their effect on the signaling pathways involved in AD neuroprotection. Recognized by their multitargeting ability, these natural compounds hold great potential in developing novel drugs for AD. Hindawi 2022-06-14 /pmc/articles/PMC9213169/ /pubmed/35746960 http://dx.doi.org/10.1155/2022/3777021 Text en Copyright © 2022 Qin Li et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Li, Qin
Rubin, Limor
Silva, Marta
Li, Shuai
Yang, Chao
Lazarovici, Philip
Zheng, Wenhua
Current Progress on Neuroprotection Induced by Artemisia, Ginseng, Astragalus, and Ginkgo Traditional Chinese Medicines for the Therapy of Alzheimer's Disease
title Current Progress on Neuroprotection Induced by Artemisia, Ginseng, Astragalus, and Ginkgo Traditional Chinese Medicines for the Therapy of Alzheimer's Disease
title_full Current Progress on Neuroprotection Induced by Artemisia, Ginseng, Astragalus, and Ginkgo Traditional Chinese Medicines for the Therapy of Alzheimer's Disease
title_fullStr Current Progress on Neuroprotection Induced by Artemisia, Ginseng, Astragalus, and Ginkgo Traditional Chinese Medicines for the Therapy of Alzheimer's Disease
title_full_unstemmed Current Progress on Neuroprotection Induced by Artemisia, Ginseng, Astragalus, and Ginkgo Traditional Chinese Medicines for the Therapy of Alzheimer's Disease
title_short Current Progress on Neuroprotection Induced by Artemisia, Ginseng, Astragalus, and Ginkgo Traditional Chinese Medicines for the Therapy of Alzheimer's Disease
title_sort current progress on neuroprotection induced by artemisia, ginseng, astragalus, and ginkgo traditional chinese medicines for the therapy of alzheimer's disease
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213169/
https://www.ncbi.nlm.nih.gov/pubmed/35746960
http://dx.doi.org/10.1155/2022/3777021
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