Cargando…

Clinical Observation and Value Analysis of Endovascular Interventional Therapy for Intracranial Venous Sinus Thrombosis

The main aim of this study was to investigate the therapeutic effect of endovascular interventional therapy on cerebral venous sinus thrombosis (CVST). 137 patients with CVST were included, 92 patients were treated with interventional therapy, and 45 patients were treated with conventional anticoagu...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Cheng, Sun, Jun, Shao, Junfei, Zhang, Xiaolu, Chen, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213190/
https://www.ncbi.nlm.nih.gov/pubmed/35747500
http://dx.doi.org/10.1155/2022/4931210
_version_ 1784730784722059264
author Wang, Cheng
Sun, Jun
Shao, Junfei
Zhang, Xiaolu
Chen, Xiang
author_facet Wang, Cheng
Sun, Jun
Shao, Junfei
Zhang, Xiaolu
Chen, Xiang
author_sort Wang, Cheng
collection PubMed
description The main aim of this study was to investigate the therapeutic effect of endovascular interventional therapy on cerebral venous sinus thrombosis (CVST). 137 patients with CVST were included, 92 patients were treated with interventional therapy, and 45 patients were treated with conventional anticoagulant therapy. Through endovascular therapy (EVT) combined with therapy, the patients were treated with EVT in combination with conventional anticoagulant therapy, and the prognosis of the two groups of patients was evaluated. The results showed that 26 patients were complicated with female-specific infections in the combined EVT group, and 7 patients had female-specific infections in the simple anticoagulant therapy (LMWH) group. In terms of central nervous system infections, the EVT group was significantly lower than the LMWH group, P < 0.001, and the difference was statistically significant. There were 2 cases of EVT involving the inferior sagittal sinus and 12 cases of LMWH involving the inferior sagittal sinus, P < 0.001, and the difference had statistical significance. Through the RANKIN scale (mRS) score, it was classified as complete recovery and good prognosis (dependent variable). The patients receiving EVT with good prognosis (96.7%) were more than those receiving simple anticoagulant therapy (84.4%), and 78.3% were completely recovered after EVT, and 77.5% were completely recovered after anticoagulant therapy. Therefore, it can be concluded that gender, malignant tumors, thrombosis, and sinuses are all risk factors affecting the prognosis of patients; both endovascular interventional therapy and anticoagulant therapy can significantly improve the prognosis of patients.
format Online
Article
Text
id pubmed-9213190
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-92131902022-06-22 Clinical Observation and Value Analysis of Endovascular Interventional Therapy for Intracranial Venous Sinus Thrombosis Wang, Cheng Sun, Jun Shao, Junfei Zhang, Xiaolu Chen, Xiang Biomed Res Int Research Article The main aim of this study was to investigate the therapeutic effect of endovascular interventional therapy on cerebral venous sinus thrombosis (CVST). 137 patients with CVST were included, 92 patients were treated with interventional therapy, and 45 patients were treated with conventional anticoagulant therapy. Through endovascular therapy (EVT) combined with therapy, the patients were treated with EVT in combination with conventional anticoagulant therapy, and the prognosis of the two groups of patients was evaluated. The results showed that 26 patients were complicated with female-specific infections in the combined EVT group, and 7 patients had female-specific infections in the simple anticoagulant therapy (LMWH) group. In terms of central nervous system infections, the EVT group was significantly lower than the LMWH group, P < 0.001, and the difference was statistically significant. There were 2 cases of EVT involving the inferior sagittal sinus and 12 cases of LMWH involving the inferior sagittal sinus, P < 0.001, and the difference had statistical significance. Through the RANKIN scale (mRS) score, it was classified as complete recovery and good prognosis (dependent variable). The patients receiving EVT with good prognosis (96.7%) were more than those receiving simple anticoagulant therapy (84.4%), and 78.3% were completely recovered after EVT, and 77.5% were completely recovered after anticoagulant therapy. Therefore, it can be concluded that gender, malignant tumors, thrombosis, and sinuses are all risk factors affecting the prognosis of patients; both endovascular interventional therapy and anticoagulant therapy can significantly improve the prognosis of patients. Hindawi 2022-06-14 /pmc/articles/PMC9213190/ /pubmed/35747500 http://dx.doi.org/10.1155/2022/4931210 Text en Copyright © 2022 Cheng Wang et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wang, Cheng
Sun, Jun
Shao, Junfei
Zhang, Xiaolu
Chen, Xiang
Clinical Observation and Value Analysis of Endovascular Interventional Therapy for Intracranial Venous Sinus Thrombosis
title Clinical Observation and Value Analysis of Endovascular Interventional Therapy for Intracranial Venous Sinus Thrombosis
title_full Clinical Observation and Value Analysis of Endovascular Interventional Therapy for Intracranial Venous Sinus Thrombosis
title_fullStr Clinical Observation and Value Analysis of Endovascular Interventional Therapy for Intracranial Venous Sinus Thrombosis
title_full_unstemmed Clinical Observation and Value Analysis of Endovascular Interventional Therapy for Intracranial Venous Sinus Thrombosis
title_short Clinical Observation and Value Analysis of Endovascular Interventional Therapy for Intracranial Venous Sinus Thrombosis
title_sort clinical observation and value analysis of endovascular interventional therapy for intracranial venous sinus thrombosis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213190/
https://www.ncbi.nlm.nih.gov/pubmed/35747500
http://dx.doi.org/10.1155/2022/4931210
work_keys_str_mv AT wangcheng clinicalobservationandvalueanalysisofendovascularinterventionaltherapyforintracranialvenoussinusthrombosis
AT sunjun clinicalobservationandvalueanalysisofendovascularinterventionaltherapyforintracranialvenoussinusthrombosis
AT shaojunfei clinicalobservationandvalueanalysisofendovascularinterventionaltherapyforintracranialvenoussinusthrombosis
AT zhangxiaolu clinicalobservationandvalueanalysisofendovascularinterventionaltherapyforintracranialvenoussinusthrombosis
AT chenxiang clinicalobservationandvalueanalysisofendovascularinterventionaltherapyforintracranialvenoussinusthrombosis