Cargando…

Biofortified tomatoes provide a new route to vitamin D sufficiency

Poor vitamin D status is a global health problem; insufficiency underpins higher risk of cancer, neurocognitive decline and all-cause mortality. Most foods contain little vitamin D and plants are very poor sources. We have engineered the accumulation of provitamin D(3) in tomato by genome editing, m...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jie, Scarano, Aurelia, Gonzalez, Nestor Mora, D’Orso, Fabio, Yue, Yajuan, Nemeth, Krisztian, Saalbach, Gerhard, Hill, Lionel, de Oliveira Martins, Carlo, Moran, Rolando, Santino, Angelo, Martin, Cathie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213236/
https://www.ncbi.nlm.nih.gov/pubmed/35606499
http://dx.doi.org/10.1038/s41477-022-01154-6
Descripción
Sumario:Poor vitamin D status is a global health problem; insufficiency underpins higher risk of cancer, neurocognitive decline and all-cause mortality. Most foods contain little vitamin D and plants are very poor sources. We have engineered the accumulation of provitamin D(3) in tomato by genome editing, modifying a duplicated section of phytosterol biosynthesis in Solanaceous plants, to provide a biofortified food with the added possibility of supplement production from waste material.