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QTL-mapping in the obese Berlin Fat Mouse identifies additional candidate genes for obesity and fatty liver disease

The Berlin Fat Mouse Inbred line (BFMI) is a model for obesity and the metabolic syndrome. This study aimed to identify genetic variants associated with liver weight, liver triglycerides, and body weight using the obese BFMI sub-line BFMI861-S1. BFMI861-S1 mice are insulin resistant and store ectopi...

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Detalles Bibliográficos
Autores principales: Delpero, Manuel, Arends, Danny, Freiberg, Aimée, Brockmann, Gudrun A., Hesse, Deike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213485/
https://www.ncbi.nlm.nih.gov/pubmed/35729251
http://dx.doi.org/10.1038/s41598-022-14316-5