Cargando…
QTL-mapping in the obese Berlin Fat Mouse identifies additional candidate genes for obesity and fatty liver disease
The Berlin Fat Mouse Inbred line (BFMI) is a model for obesity and the metabolic syndrome. This study aimed to identify genetic variants associated with liver weight, liver triglycerides, and body weight using the obese BFMI sub-line BFMI861-S1. BFMI861-S1 mice are insulin resistant and store ectopi...
Autores principales: | Delpero, Manuel, Arends, Danny, Freiberg, Aimée, Brockmann, Gudrun A., Hesse, Deike |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213485/ https://www.ncbi.nlm.nih.gov/pubmed/35729251 http://dx.doi.org/10.1038/s41598-022-14316-5 |
Ejemplares similares
-
Identification of four novel QTL linked to the metabolic syndrome in the Berlin Fat Mouse
por: Delpero, Manuel, et al.
Publicado: (2021) -
A deletion containing a CTCF-element in intron 8 of the Bbs7 gene is partially responsible for juvenile obesity in the Berlin Fat Mouse
por: Krause, Florian, et al.
Publicado: (2021) -
A 5′ UTR Mutation Contributes to Down-Regulation of Bbs7 in the Berlin Fat Mouse
por: Mohebian, Kourosh, et al.
Publicado: (2022) -
Transmission distortion and genetic incompatibilities between alleles in a multigenerational mouse advanced intercross line
por: Arends, Danny, et al.
Publicado: (2021) -
Genetic and diet effects on Ppar-α and Ppar-γ signaling pathways in the Berlin Fat Mouse Inbred line with genetic predisposition for obesity
por: Wagener, Asja, et al.
Publicado: (2010)