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Anti-HER2 scFv-CCL19-IL7 recombinant protein inhibited gastric tumor growth in vivo
HER-2 targeted therapies, such as monoclonal antibodies (mAbs) and CAR-T cell therapy have been applied in the treatment of various of cancers. However, the anti-HER2 CAR-T cell therapy are limited by its expensive production procedure and fatal side effects such as cytokine storm or “On target, off...
Autores principales: | Zhang, Haiqiang, Ye, Xueshuai, Wen, Junye, Cai, Ziqi, Li, Yang, Zhang, Mengya, Shen, Li, Cai, Jianhui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213520/ https://www.ncbi.nlm.nih.gov/pubmed/35729189 http://dx.doi.org/10.1038/s41598-022-14336-1 |
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