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Anti-HER2 scFv-CCL19-IL7 recombinant protein inhibited gastric tumor growth in vivo

HER-2 targeted therapies, such as monoclonal antibodies (mAbs) and CAR-T cell therapy have been applied in the treatment of various of cancers. However, the anti-HER2 CAR-T cell therapy are limited by its expensive production procedure and fatal side effects such as cytokine storm or “On target, off...

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Detalles Bibliográficos
Autores principales: Zhang, Haiqiang, Ye, Xueshuai, Wen, Junye, Cai, Ziqi, Li, Yang, Zhang, Mengya, Shen, Li, Cai, Jianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213520/
https://www.ncbi.nlm.nih.gov/pubmed/35729189
http://dx.doi.org/10.1038/s41598-022-14336-1

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