Kir2.1-mediated membrane potential promotes nutrient acquisition and inflammation through regulation of nutrient transporters

Immunometabolism contributes to inflammation, but how activated macrophages acquire extracellular nutrients to fuel inflammation is largely unknown. Here, we show that the plasma membrane potential (V(m)) of macrophages mediated by Kir2.1, an inwardly-rectifying K(+) channel, is an important determi...

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Detalles Bibliográficos
Autores principales: Yu, Weiwei, Wang, Zhen, Yu, Xiafei, Zhao, Yonghui, Xie, Zili, Zhang, Kailian, Chi, Zhexu, Chen, Sheng, Xu, Ting, Jiang, Danlu, Guo, Xingchen, Li, Mobai, Zhang, Jian, Fang, Hui, Yang, Dehang, Guo, Yuxian, Yang, Xuyan, Zhang, Xue, Wu, Yingliang, Yang, Wei, Wang, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213538/
https://www.ncbi.nlm.nih.gov/pubmed/35729093
http://dx.doi.org/10.1038/s41467-022-31149-y

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