A retrotransposon storm marks clinical phenoconversion to late-onset Alzheimer’s disease

Recent reports have suggested that the reactivation of otherwise transcriptionally silent transposable elements (TEs) might induce brain degeneration, either by dysregulating the expression of genes and pathways implicated in cognitive decline and dementia or through the induction of immune-mediated...

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Detalles Bibliográficos
Autores principales: Macciardi, Fabio, Giulia Bacalini, Maria, Miramontes, Ricardo, Boattini, Alessio, Taccioli, Cristian, Modenini, Giorgia, Malhas, Rond, Anderlucci, Laura, Gusev, Yuriy, Gross, Thomas J., Padilla, Robert M., Fiandaca, Massimo S., Head, Elizabeth, Guffanti, Guia, Federoff, Howard J., Mapstone, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213607/
https://www.ncbi.nlm.nih.gov/pubmed/35585302
http://dx.doi.org/10.1007/s11357-022-00580-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213607/
https://www.ncbi.nlm.nih.gov/pubmed/35585302
http://dx.doi.org/10.1007/s11357-022-00580-w

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