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A retrotransposon storm marks clinical phenoconversion to late-onset Alzheimer’s disease
Recent reports have suggested that the reactivation of otherwise transcriptionally silent transposable elements (TEs) might induce brain degeneration, either by dysregulating the expression of genes and pathways implicated in cognitive decline and dementia or through the induction of immune-mediated...
Autores principales: | Macciardi, Fabio, Giulia Bacalini, Maria, Miramontes, Ricardo, Boattini, Alessio, Taccioli, Cristian, Modenini, Giorgia, Malhas, Rond, Anderlucci, Laura, Gusev, Yuriy, Gross, Thomas J., Padilla, Robert M., Fiandaca, Massimo S., Head, Elizabeth, Guffanti, Guia, Federoff, Howard J., Mapstone, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213607/ https://www.ncbi.nlm.nih.gov/pubmed/35585302 http://dx.doi.org/10.1007/s11357-022-00580-w |
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