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Transglutaminase-2 mediates acquisition of neratinib resistance in metastatic breast cancer
Acquisition of resistance to targeted therapies remains a major clinical obstacle for the HER2(+) subtype of breast cancer. Using an isogeneic progression series of HER2(+) breast cancer metastasis we demonstrate that metastatic cells have an increased capacity to acquire resistance to the covalent,...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Nature Singapore
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213622/ https://www.ncbi.nlm.nih.gov/pubmed/35729402 http://dx.doi.org/10.1186/s43556-022-00079-y |