SGLT2 inhibition attenuates arterial dysfunction and decreases vascular F-actin content and expression of proteins associated with oxidative stress in aged mice

Aging of the vasculature is characterized by endothelial dysfunction and arterial stiffening, two key events in the pathogenesis of cardiovascular disease (CVD). Treatment with sodium glucose transporter 2 (SGLT2) inhibitors is now known to decrease cardiovascular morbidity and mortality in type 2 d...

Descripción completa

Detalles Bibliográficos
Autores principales: Soares, Rogerio N., Ramirez-Perez, Francisco I., Cabral-Amador, Francisco J., Morales-Quinones, Mariana, Foote, Christopher A., Ghiarone, Thaysa, Sharma, Neekun, Power, Gavin, Smith, James A., Rector, R. Scott, Martinez-Lemus, Luis A., Padilla, Jaume, Manrique-Acevedo, Camila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213629/
https://www.ncbi.nlm.nih.gov/pubmed/35426600
http://dx.doi.org/10.1007/s11357-022-00563-x

Ejemplares similares

Ejemplares similares