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Structural basis of the IL-1 receptor TIR domain-mediated IL-1 signaling

The cytoplasmic Toll/interleukin-1 receptor (TIR) domains of IL-1 receptors (IL-1Rs) are evolutionally conserved and essential for transmitting signals. IL-1RAcP is a shared co-receptor in the IL-1R family for signaling. Its splicing form IL-1RAcPb contains a different TIR domain and is unable to tr...

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Detalles Bibliográficos
Autores principales:	Zhou, Jianjie, Xiao, Yu, Ren, Yifei, Ge, Jiwan, Wang, Xinquan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213720/ https://www.ncbi.nlm.nih.gov/pubmed/35754719 http://dx.doi.org/10.1016/j.isci.2022.104508

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