Ripk3 signaling regulates HSCs during stress and represses radiation-induced leukemia in mice

Receptor-interacting protein kinase 3 (Ripk3) is one of the critical mediators of inflammatory cytokine-stimulated signaling. Here we show that Ripk3 signaling selectively regulates both the number and the function of hematopoietic stem cells (HSCs) during stress conditions. Ripk3 signaling is not r...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Luo, Huacheng, Ni, Hong-Min, Liu, Shanhui, Xing, Hongyun, Zhang, Jun, Sellin, Mark, Breslin, S.J., Peter, Wei, Wei, Denning, Mitchell F., Small, William, Ding, Wen-Xing, Huang, Suming, Zhang, Jiwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213819/
https://www.ncbi.nlm.nih.gov/pubmed/35561683
http://dx.doi.org/10.1016/j.stemcr.2022.04.009

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