Inhibition of the Protein Arginine Methyltransferase PRMT5 in High-Risk Multiple Myeloma as a Novel Treatment Approach

Multiple myeloma (MM) is an incurable clonal plasma cell malignancy. Subsets of patients have high-risk features linked with dismal outcome. Therefore, the need for effective therapeutic options remains high. Here, we used bio-informatic tools to identify novel targets involved in DNA repair and epi...

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Detalles Bibliográficos
Autores principales: Vlummens, Philip, Verhulst, Stefaan, De Veirman, Kim, Maes, Anke, Menu, Eline, Moreaux, Jérome, De Boussac, Hugues, Robert, Nicolas, De Bruyne, Elke, Hose, Dirk, Offner, Fritz, Vanderkerken, Karin, Maes, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213887/
https://www.ncbi.nlm.nih.gov/pubmed/35757005
http://dx.doi.org/10.3389/fcell.2022.879057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213887/
https://www.ncbi.nlm.nih.gov/pubmed/35757005
http://dx.doi.org/10.3389/fcell.2022.879057

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