Cargando…

Synthesis of Benzylidene Analogs of Oleanolic Acid as Potential α-Glucosidase and α-Amylase Inhibitors

A series of benzylidene analogs of oleanolic acid 4a∼4s were synthesized and assessed for their α-glucosidase and α-amylase inhibitory activities. The results presented that all synthesized analogs exhibited excellent-to-moderate inhibitory effects on α-glucosidase and α-amylase. Analog 4i showed th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ke, Jun-Jie, Lin, Jing, Zhang, Xin, Wu, Xiao-Zheng, Zheng, Ying-Ying, Hu, Chun-Mei, Kang, Yu, Zhang, Kun, Xiong, Zhuang, Ma, Zhi-Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213889/ https://www.ncbi.nlm.nih.gov/pubmed/35755256 http://dx.doi.org/10.3389/fchem.2022.911232

Ejemplares similares

Synthesis and bioactivities evaluation of oleanolic acid oxime ester derivatives as α-glucosidase and α-amylase inhibitors
por: Deng, Xu-Yang, et al.
Publicado: (2022)

In vitro and in silico studies of bis (indol-3-yl) methane derivatives as potential α-glucosidase and α-amylase inhibitors
por: Zheng, Peng-Fei, et al.
Publicado: (2021)

Momilactones A and B Are α-Amylase and α-Glucosidase Inhibitors
por: Quan, Nguyen Van, et al.
Publicado: (2019)

Dietary Polyphenols as Natural Inhibitors of α-Amylase and α-Glucosidase
por: Ćorković, Ina, et al.
Publicado: (2022)

Synthesis and inhibitory activity of N-acetylpyrrolidine derivatives on α-glucosidase and α-amylase
por: Sansenya, Sompong, et al.
Publicado: (2020)

Synthesis and Molecular Docking Studies of Alkoxy- and Imidazole-Substituted Xanthones as α-Amylase and α-Glucosidase Inhibitors
por: Aguila-Muñoz, Dolores G., et al.
Publicado: (2023)

Synthesis and biological evaluation of novel ursolic acid analogues as potential α-glucosidase inhibitors
por: Wu, Pan-Pan, et al.
Publicado: (2017)

Inhibition of α-glucosidase, α-amylase, and aldose reductase by potato polyphenolic compounds
por: Kalita, Diganta, et al.
Publicado: (2018)

The α-Amylase and α-Glucosidase Inhibition Capacity of Grape Pomace: A Review
por: Cisneros-Yupanqui, Miluska, et al.
Publicado: (2022)

Influence of gallic acid on α-amylase and α-glucosidase inhibitory properties of acarbose
por: Oboh, Ganiyu, et al.
Publicado: (2016)

A Review of the In Vitro Inhibition of α-Amylase and α-Glucosidase by Chalcone Derivatives
por: Tran, Thanh-Dao, et al.
Publicado: (2023)

Design, Synthesis, In Silico Testing, and In Vitro Evaluation of Thiazolidinone-Based Benzothiazole Derivatives as Inhibitors of α-Amylase and α-Glucosidase
por: Khan, Shoaib, et al.
Publicado: (2022)

Inhibitors of α‐amylase and α‐glucosidase: Potential linkage for whole cereal foods on prevention of hyperglycemia
por: Gong, Lingxiao, et al.
Publicado: (2020)

Synthesis and Evaluation of Coumarin-Chalcone Derivatives as α-Glucosidase Inhibitors
por: Hu, Chun-Mei, et al.
Publicado: (2022)

Hypoglycemic Efficacy of Docking Selected Natural Compounds against α-Glucosidase and α-Amylase
por: Riyaphan, Jirawat, et al.
Publicado: (2018)

Spiroindolone Analogues as Potential Hypoglycemic with Dual Inhibitory Activity on α-Amylase and α-Glucosidase
por: Altowyan, Mezna Saleh, et al.
Publicado: (2019)

α-Glucosidase, α-Amylase and Antioxidant Evaluations of Isolated Bioactives from Wild Strawberry
por: Huneif, Mohammed A., et al.
Publicado: (2022)

Novel oxadiazole derivatives as potent inhibitors of α-amylase and α-glucosidase enzymes: Synthesis, in vitro evaluation, and molecular docking studies
por: Bukhari, Asma, et al.
Publicado: (2021)

New quinoline-based triazole hybrid analogs as effective inhibitors of α-amylase and α-glucosidase: Preparation, in vitro evaluation, and molecular docking along with in silico studies
por: Khan, Yousaf, et al.
Publicado: (2022)

Metabolites extracted from microorganisms as potential inhibitors of glycosidases (α-glucosidase and α-amylase): A review
por: Wang, Xiaojing, et al.
Publicado: (2022)

Inhibition Kinetics and Theoretical Studies on Zanthoxylum chalybeum Engl. Dual Inhibitors of α-Glucosidase and α-Amylase
por: Kimani, Njogu M., et al.
Publicado: (2023)

Biochemical and Phylogenetic Analysis of Italian Phaseolus vulgaris Cultivars as Sources of α-Amylase and α-Glucosidase Inhibitors
por: Peddio, Stefania, et al.
Publicado: (2023)

Novel C-2 Symmetric Molecules as α-Glucosidase and α-Amylase Inhibitors: Design, Synthesis, Kinetic Evaluation, Molecular Docking and Pharmacokinetics
por: Shahzad, Danish, et al.
Publicado: (2019)

Benzimidazole Bearing Thiosemicarbazone Derivatives Act as Potent α-Amylase and α-Glucosidase Inhibitors; Synthesis, Bioactivity Screening and Molecular Docking Study
por: Ullah, Hayat, et al.
Publicado: (2022)

Synthesis of an amantadine-based novel Schiff base and its transition metal complexes as potential ALP, α-amylase, and α-glucosidase inhibitors
por: Ajaz, Aliya, et al.
Publicado: (2023)

Synthesis, in vitro biological assessment, and molecular docking study of benzimidazole-based thiadiazole derivatives as dual inhibitors of α-amylase and α-glucosidase
por: Khan, Shoaib, et al.
Publicado: (2023)

In vitro α -amylase and α-glucosidase inhibitory potential of Trigonella foenum-graecum leaves extract
por: Ganeshpurkar, Aditya, et al.
Publicado: (2013)

Modes of Inhibition of α-Amylase and α-Glucosidase by Aqueous Extract of Morinda lucida Benth Leaf
por: Kazeem, M. I., et al.
Publicado: (2013)

In vitro α-amylase and α-glucosidase inhibitory effects and cytotoxic activity of Albizia antunesiana extracts
por: Chipiti, Talent, et al.
Publicado: (2015)

In Vitro Inhibition of α-Amylase and α-Glucosidase by Extracts from Psiadia punctulata and Meriandra bengalensis
por: Kidane, Yosief, et al.
Publicado: (2018)

The α-amylase and α-glucosidase inhibitory activities of the dichloromethane extracts and constituents of Ferulago bracteata roots
por: Karakaya, Songül, et al.
Publicado: (2017)

Investigation into the Thermal Response and Pharmacological Activity of Substituted Schiff Bases on α-Amylase and α-Glucosidase
por: Okoli, Bamidele Joseph, et al.
Publicado: (2018)

Antioxidant, α-Amylase and α-Glucosidase Inhibitory Activities and Potential Constituents of Canarium tramdenum Bark
por: Quan, Nguyen Van, et al.
Publicado: (2019)

Effect of storage time on antioxidant activity and inhibition on α‐Amylase and α‐Glucosidase of white tea
por: Xu, Ping, et al.
Publicado: (2019)

In Vitro Inhibitory Effects of Organic Acids Identified in Commercial Vinegars on α-Amylase and α-Glucosidase
por: Noh, Young-Hee, et al.
Publicado: (2020)

In vitro and in vivo inhibitory effects of Carica papaya seed on α-amylase and α-glucosidase enzymes
por: Agada, Reuben, et al.
Publicado: (2020)

Phytochemical Screening, Antioxidant, and Inhibition Activity of Picrorhiza kurroa Against α-Amylase and α-Glucosidase
por: Nisar, Jaweria, et al.
Publicado: (2022)

Synthesis and Inhibitory Effect of Some Indole‐Pyrimidine Based Hybrid Heterocycles on α‐Glucosidase and α‐Amylase as Potential Hypoglycemic Agents
por: Badria, Farid A., et al.
Publicado: (2019)

Novel N′-substituted benzylidene benzohydrazides linked to 1,2,3-triazoles: potent α-glucosidase inhibitors
por: Saeedi, Mina, et al.
Publicado: (2023)

In Silico Approaches to Identify Polyphenol Compounds as α-Glucosidase and α-Amylase Inhibitors against Type-II Diabetes
por: Riyaphan, Jirawat, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rp80eg2thekrvasf8b1s7dfrrh