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YPD-30, a prodrug of YPD-29B, is an oral small-molecule inhibitor targeting PD-L1 for the treatment of human cancer
PD-1 and PD-L1 antibodies have brought about extraordinary clinical benefits for cancer patients, and their indications are expanding incessantly. Currently, most PD-1/PD-L1 agents are administered intravenously, which may be uncomfortable for some cancer patients. Herein, we develop a novel oral-de...
Autores principales: | Lai, Fangfang, Ji, Ming, Huang, Lei, Wang, Yunchen, Xue, Nina, Du, Tingting, Dong, Kai, Yao, Xiaoqing, Jin, Jing, Feng, Zhiqiang, Chen, Xiaoguang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214057/ https://www.ncbi.nlm.nih.gov/pubmed/35755282 http://dx.doi.org/10.1016/j.apsb.2022.02.031 |
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