Molecular profiling of stem cell-derived retinal pigment epithelial cell differentiation established for clinical translation

Human embryonic stem cell-derived retinal pigment epithelial cells (hESC-RPE) are a promising cell source to treat age-related macular degeneration (AMD). Despite several ongoing clinical studies, a detailed mapping of transient cellular states during in vitro differentiation has not been performed....

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Detalles Bibliográficos
Autores principales: Petrus-Reurer, Sandra, Lederer, Alex R., Baqué-Vidal, Laura, Douagi, Iyadh, Pannagel, Belinda, Khven, Irina, Aronsson, Monica, Bartuma, Hammurabi, Wagner, Magdalena, Wrona, Andreas, Efstathopoulos, Paschalis, Jaberi, Elham, Willenbrock, Hanni, Shimizu, Yutaka, Villaescusa, J. Carlos, André, Helder, Sundstrӧm, Erik, Bhaduri, Aparna, Kriegstein, Arnold, Kvanta, Anders, La Manno, Gioele, Lanner, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214069/
https://www.ncbi.nlm.nih.gov/pubmed/35705015
http://dx.doi.org/10.1016/j.stemcr.2022.05.005

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