Autism NPCs from both idiopathic and CNV 16p11.2 deletion patients exhibit dysregulation of proliferation and mitogenic responses

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Neural precursor cell (NPC) dysfunction has been consistently implicated in autism. Induced pluripotent stem cell (iPSC)-derived NPCs from two autism groups (three idiopathic [I-ASD] and two 16p11.2 deletion [16pDel]) were used to investigate if proliferation is commonly disrupted. All five individu...

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Detalles Bibliográficos
Autores principales: Connacher, Robert, Williams, Madeline, Prem, Smrithi, Yeung, Percy L., Matteson, Paul, Mehta, Monal, Markov, Anna, Peng, Cynthia, Zhou, Xiaofeng, McDermott, Courtney R., Pang, Zhiping P., Flax, Judy, Brzustowicz, Linda, Lu, Che-Wei, Millonig, James H., DiCicco-Bloom, Emanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214070/
https://www.ncbi.nlm.nih.gov/pubmed/35623351
http://dx.doi.org/10.1016/j.stemcr.2022.04.019
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