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Chemotherapeutic nanomaterials in tumor boundary delineation: Prospects for effective tumor treatment
Accurately delineating tumor boundaries is key to predicting survival rates of cancer patients and assessing response of tumor microenvironment to various therapeutic techniques such as chemotherapy and radiotherapy. This review discusses various strategies that have been deployed to accurately deli...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214073/ https://www.ncbi.nlm.nih.gov/pubmed/35755279 http://dx.doi.org/10.1016/j.apsb.2022.02.016 |
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author | Akakuru, Ozioma Udochukwu Zhang, Zhoujing Iqbal, M. Zubair Zhu, Chengjie Zhang, Yewei Wu, Aiguo |
author_facet | Akakuru, Ozioma Udochukwu Zhang, Zhoujing Iqbal, M. Zubair Zhu, Chengjie Zhang, Yewei Wu, Aiguo |
author_sort | Akakuru, Ozioma Udochukwu |
collection | PubMed |
description | Accurately delineating tumor boundaries is key to predicting survival rates of cancer patients and assessing response of tumor microenvironment to various therapeutic techniques such as chemotherapy and radiotherapy. This review discusses various strategies that have been deployed to accurately delineate tumor boundaries with particular emphasis on the potential of chemotherapeutic nanomaterials in tumor boundary delineation. It also compiles the types of tumors that have been successfully delineated by currently available strategies. Finally, the challenges that still abound in accurate tumor boundary delineation are presented alongside possible perspective strategies to either ameliorate or solve the problems. It is expected that the information communicated herein will form the first compendious baseline information on tumor boundary delineation with chemotherapeutic nanomaterials and provide useful insights into future possible paths to advancing current available tumor boundary delineation approaches to achieve efficacious tumor therapy. |
format | Online Article Text |
id | pubmed-9214073 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-92140732022-06-23 Chemotherapeutic nanomaterials in tumor boundary delineation: Prospects for effective tumor treatment Akakuru, Ozioma Udochukwu Zhang, Zhoujing Iqbal, M. Zubair Zhu, Chengjie Zhang, Yewei Wu, Aiguo Acta Pharm Sin B Review Accurately delineating tumor boundaries is key to predicting survival rates of cancer patients and assessing response of tumor microenvironment to various therapeutic techniques such as chemotherapy and radiotherapy. This review discusses various strategies that have been deployed to accurately delineate tumor boundaries with particular emphasis on the potential of chemotherapeutic nanomaterials in tumor boundary delineation. It also compiles the types of tumors that have been successfully delineated by currently available strategies. Finally, the challenges that still abound in accurate tumor boundary delineation are presented alongside possible perspective strategies to either ameliorate or solve the problems. It is expected that the information communicated herein will form the first compendious baseline information on tumor boundary delineation with chemotherapeutic nanomaterials and provide useful insights into future possible paths to advancing current available tumor boundary delineation approaches to achieve efficacious tumor therapy. Elsevier 2022-06 2022-02-23 /pmc/articles/PMC9214073/ /pubmed/35755279 http://dx.doi.org/10.1016/j.apsb.2022.02.016 Text en © 2022 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Akakuru, Ozioma Udochukwu Zhang, Zhoujing Iqbal, M. Zubair Zhu, Chengjie Zhang, Yewei Wu, Aiguo Chemotherapeutic nanomaterials in tumor boundary delineation: Prospects for effective tumor treatment |
title | Chemotherapeutic nanomaterials in tumor boundary delineation: Prospects for effective tumor treatment |
title_full | Chemotherapeutic nanomaterials in tumor boundary delineation: Prospects for effective tumor treatment |
title_fullStr | Chemotherapeutic nanomaterials in tumor boundary delineation: Prospects for effective tumor treatment |
title_full_unstemmed | Chemotherapeutic nanomaterials in tumor boundary delineation: Prospects for effective tumor treatment |
title_short | Chemotherapeutic nanomaterials in tumor boundary delineation: Prospects for effective tumor treatment |
title_sort | chemotherapeutic nanomaterials in tumor boundary delineation: prospects for effective tumor treatment |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214073/ https://www.ncbi.nlm.nih.gov/pubmed/35755279 http://dx.doi.org/10.1016/j.apsb.2022.02.016 |
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