Preferential uptake of SARS-CoV-2 by pericytes potentiates vascular damage and permeability in an organoid model of the microvasculature

AIMS: Thrombotic complications and vasculopathy have been extensively associated with severe COVID-19 infection; however, the mechanisms inducing endotheliitis and the disruption of endothelial integrity in the microcirculation are poorly understood. We hypothesized that within the vessel wall, peri...

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Detalles Bibliográficos
Autores principales: Khan, Abdullah O, Reyat, Jasmeet S, Hill, Harriet, Bourne, Joshua H, Colicchia, Martina, Newby, Maddy L, Allen, Joel D, Crispin, Max, Youd, Esther, Murray, Paul G, Taylor, Graham, Stamataki, Zania, Richter, Alex G, Cunningham, Adam F, Pugh, Matthew, Rayes, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214165/
https://www.ncbi.nlm.nih.gov/pubmed/35709328
http://dx.doi.org/10.1093/cvr/cvac097

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