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Pore Strategy Design of a Novel NiTi-Nb Biomedical Porous Scaffold Based on a Triply Periodic Minimal Surface
The pore strategy is one of the important factors affecting the biomedical porous scaffold at the same porosity. In this work, porous scaffolds were designed based on the triply periodic minimal surface (TPMS) structure under the same porosity and different pore strategies (pore size and size contin...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214207/ https://www.ncbi.nlm.nih.gov/pubmed/35757802 http://dx.doi.org/10.3389/fbioe.2022.910475 |
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author | Lv, Yuting Liu, Guohao Wang, Binghao Tang, Yujin Lin, Zhengjie Liu, Jia Wei, Guijiang Wang, Liqiang |
author_facet | Lv, Yuting Liu, Guohao Wang, Binghao Tang, Yujin Lin, Zhengjie Liu, Jia Wei, Guijiang Wang, Liqiang |
author_sort | Lv, Yuting |
collection | PubMed |
description | The pore strategy is one of the important factors affecting the biomedical porous scaffold at the same porosity. In this work, porous scaffolds were designed based on the triply periodic minimal surface (TPMS) structure under the same porosity and different pore strategies (pore size and size continuous gradient distribution) and were successfully prepared using a novel Ni(46.5)Ti(44.5)Nb(9) alloy and selective laser melting (SLM) technology. After that, the effects of the pore strategies on the microstructure, mechanical properties, and permeability of porous scaffolds were systematically investigated. The results showed that the Ni(46.5)Ti(44.5)Nb(9) scaffolds have a low elastic modulus (0.80–1.05 GPa) and a high ductility (15.3–19.1%) compared with previous works. The pore size has little effect on their mechanical properties, but increasing the pore size significantly improves the permeability due to the decrease in specific surfaces. The continuous gradient distribution of the pore size changes the material distribution of the scaffold, and the smaller porosity structure has a better load-bearing capacity and contributes primarily to the high compression strength. The local high porosity structure bears more fluid flow, which can improve the permeability of the overall scaffold. This work can provide theoretical guidance for the design of porous scaffolds. |
format | Online Article Text |
id | pubmed-9214207 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-92142072022-06-23 Pore Strategy Design of a Novel NiTi-Nb Biomedical Porous Scaffold Based on a Triply Periodic Minimal Surface Lv, Yuting Liu, Guohao Wang, Binghao Tang, Yujin Lin, Zhengjie Liu, Jia Wei, Guijiang Wang, Liqiang Front Bioeng Biotechnol Bioengineering and Biotechnology The pore strategy is one of the important factors affecting the biomedical porous scaffold at the same porosity. In this work, porous scaffolds were designed based on the triply periodic minimal surface (TPMS) structure under the same porosity and different pore strategies (pore size and size continuous gradient distribution) and were successfully prepared using a novel Ni(46.5)Ti(44.5)Nb(9) alloy and selective laser melting (SLM) technology. After that, the effects of the pore strategies on the microstructure, mechanical properties, and permeability of porous scaffolds were systematically investigated. The results showed that the Ni(46.5)Ti(44.5)Nb(9) scaffolds have a low elastic modulus (0.80–1.05 GPa) and a high ductility (15.3–19.1%) compared with previous works. The pore size has little effect on their mechanical properties, but increasing the pore size significantly improves the permeability due to the decrease in specific surfaces. The continuous gradient distribution of the pore size changes the material distribution of the scaffold, and the smaller porosity structure has a better load-bearing capacity and contributes primarily to the high compression strength. The local high porosity structure bears more fluid flow, which can improve the permeability of the overall scaffold. This work can provide theoretical guidance for the design of porous scaffolds. Frontiers Media S.A. 2022-06-08 /pmc/articles/PMC9214207/ /pubmed/35757802 http://dx.doi.org/10.3389/fbioe.2022.910475 Text en Copyright © 2022 Lv, Liu, Wang, Tang, Lin, Liu, Wei and Wang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Bioengineering and Biotechnology Lv, Yuting Liu, Guohao Wang, Binghao Tang, Yujin Lin, Zhengjie Liu, Jia Wei, Guijiang Wang, Liqiang Pore Strategy Design of a Novel NiTi-Nb Biomedical Porous Scaffold Based on a Triply Periodic Minimal Surface |
title | Pore Strategy Design of a Novel NiTi-Nb Biomedical Porous Scaffold Based on a Triply Periodic Minimal Surface |
title_full | Pore Strategy Design of a Novel NiTi-Nb Biomedical Porous Scaffold Based on a Triply Periodic Minimal Surface |
title_fullStr | Pore Strategy Design of a Novel NiTi-Nb Biomedical Porous Scaffold Based on a Triply Periodic Minimal Surface |
title_full_unstemmed | Pore Strategy Design of a Novel NiTi-Nb Biomedical Porous Scaffold Based on a Triply Periodic Minimal Surface |
title_short | Pore Strategy Design of a Novel NiTi-Nb Biomedical Porous Scaffold Based on a Triply Periodic Minimal Surface |
title_sort | pore strategy design of a novel niti-nb biomedical porous scaffold based on a triply periodic minimal surface |
topic | Bioengineering and Biotechnology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214207/ https://www.ncbi.nlm.nih.gov/pubmed/35757802 http://dx.doi.org/10.3389/fbioe.2022.910475 |
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