Cargando…

Pore Strategy Design of a Novel NiTi-Nb Biomedical Porous Scaffold Based on a Triply Periodic Minimal Surface

The pore strategy is one of the important factors affecting the biomedical porous scaffold at the same porosity. In this work, porous scaffolds were designed based on the triply periodic minimal surface (TPMS) structure under the same porosity and different pore strategies (pore size and size contin...

Descripción completa

Detalles Bibliográficos
Autores principales: Lv, Yuting, Liu, Guohao, Wang, Binghao, Tang, Yujin, Lin, Zhengjie, Liu, Jia, Wei, Guijiang, Wang, Liqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214207/
https://www.ncbi.nlm.nih.gov/pubmed/35757802
http://dx.doi.org/10.3389/fbioe.2022.910475
_version_ 1784730963201228800
author Lv, Yuting
Liu, Guohao
Wang, Binghao
Tang, Yujin
Lin, Zhengjie
Liu, Jia
Wei, Guijiang
Wang, Liqiang
author_facet Lv, Yuting
Liu, Guohao
Wang, Binghao
Tang, Yujin
Lin, Zhengjie
Liu, Jia
Wei, Guijiang
Wang, Liqiang
author_sort Lv, Yuting
collection PubMed
description The pore strategy is one of the important factors affecting the biomedical porous scaffold at the same porosity. In this work, porous scaffolds were designed based on the triply periodic minimal surface (TPMS) structure under the same porosity and different pore strategies (pore size and size continuous gradient distribution) and were successfully prepared using a novel Ni(46.5)Ti(44.5)Nb(9) alloy and selective laser melting (SLM) technology. After that, the effects of the pore strategies on the microstructure, mechanical properties, and permeability of porous scaffolds were systematically investigated. The results showed that the Ni(46.5)Ti(44.5)Nb(9) scaffolds have a low elastic modulus (0.80–1.05 GPa) and a high ductility (15.3–19.1%) compared with previous works. The pore size has little effect on their mechanical properties, but increasing the pore size significantly improves the permeability due to the decrease in specific surfaces. The continuous gradient distribution of the pore size changes the material distribution of the scaffold, and the smaller porosity structure has a better load-bearing capacity and contributes primarily to the high compression strength. The local high porosity structure bears more fluid flow, which can improve the permeability of the overall scaffold. This work can provide theoretical guidance for the design of porous scaffolds.
format Online
Article
Text
id pubmed-9214207
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-92142072022-06-23 Pore Strategy Design of a Novel NiTi-Nb Biomedical Porous Scaffold Based on a Triply Periodic Minimal Surface Lv, Yuting Liu, Guohao Wang, Binghao Tang, Yujin Lin, Zhengjie Liu, Jia Wei, Guijiang Wang, Liqiang Front Bioeng Biotechnol Bioengineering and Biotechnology The pore strategy is one of the important factors affecting the biomedical porous scaffold at the same porosity. In this work, porous scaffolds were designed based on the triply periodic minimal surface (TPMS) structure under the same porosity and different pore strategies (pore size and size continuous gradient distribution) and were successfully prepared using a novel Ni(46.5)Ti(44.5)Nb(9) alloy and selective laser melting (SLM) technology. After that, the effects of the pore strategies on the microstructure, mechanical properties, and permeability of porous scaffolds were systematically investigated. The results showed that the Ni(46.5)Ti(44.5)Nb(9) scaffolds have a low elastic modulus (0.80–1.05 GPa) and a high ductility (15.3–19.1%) compared with previous works. The pore size has little effect on their mechanical properties, but increasing the pore size significantly improves the permeability due to the decrease in specific surfaces. The continuous gradient distribution of the pore size changes the material distribution of the scaffold, and the smaller porosity structure has a better load-bearing capacity and contributes primarily to the high compression strength. The local high porosity structure bears more fluid flow, which can improve the permeability of the overall scaffold. This work can provide theoretical guidance for the design of porous scaffolds. Frontiers Media S.A. 2022-06-08 /pmc/articles/PMC9214207/ /pubmed/35757802 http://dx.doi.org/10.3389/fbioe.2022.910475 Text en Copyright © 2022 Lv, Liu, Wang, Tang, Lin, Liu, Wei and Wang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Lv, Yuting
Liu, Guohao
Wang, Binghao
Tang, Yujin
Lin, Zhengjie
Liu, Jia
Wei, Guijiang
Wang, Liqiang
Pore Strategy Design of a Novel NiTi-Nb Biomedical Porous Scaffold Based on a Triply Periodic Minimal Surface
title Pore Strategy Design of a Novel NiTi-Nb Biomedical Porous Scaffold Based on a Triply Periodic Minimal Surface
title_full Pore Strategy Design of a Novel NiTi-Nb Biomedical Porous Scaffold Based on a Triply Periodic Minimal Surface
title_fullStr Pore Strategy Design of a Novel NiTi-Nb Biomedical Porous Scaffold Based on a Triply Periodic Minimal Surface
title_full_unstemmed Pore Strategy Design of a Novel NiTi-Nb Biomedical Porous Scaffold Based on a Triply Periodic Minimal Surface
title_short Pore Strategy Design of a Novel NiTi-Nb Biomedical Porous Scaffold Based on a Triply Periodic Minimal Surface
title_sort pore strategy design of a novel niti-nb biomedical porous scaffold based on a triply periodic minimal surface
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214207/
https://www.ncbi.nlm.nih.gov/pubmed/35757802
http://dx.doi.org/10.3389/fbioe.2022.910475
work_keys_str_mv AT lvyuting porestrategydesignofanovelnitinbbiomedicalporousscaffoldbasedonatriplyperiodicminimalsurface
AT liuguohao porestrategydesignofanovelnitinbbiomedicalporousscaffoldbasedonatriplyperiodicminimalsurface
AT wangbinghao porestrategydesignofanovelnitinbbiomedicalporousscaffoldbasedonatriplyperiodicminimalsurface
AT tangyujin porestrategydesignofanovelnitinbbiomedicalporousscaffoldbasedonatriplyperiodicminimalsurface
AT linzhengjie porestrategydesignofanovelnitinbbiomedicalporousscaffoldbasedonatriplyperiodicminimalsurface
AT liujia porestrategydesignofanovelnitinbbiomedicalporousscaffoldbasedonatriplyperiodicminimalsurface
AT weiguijiang porestrategydesignofanovelnitinbbiomedicalporousscaffoldbasedonatriplyperiodicminimalsurface
AT wangliqiang porestrategydesignofanovelnitinbbiomedicalporousscaffoldbasedonatriplyperiodicminimalsurface