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Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombe

The fission yeast Schizosaccharomyces pombe employs two main strategies to adapt to the environment and survive when starved for nutrients. The strategies employ sporulation via sexual differentiation and extension of the chronological lifespan. When a cell is exposed to nutrient starvation in the p...

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Autores principales: Ohtsuka, Hokuto, Imada, Kazuki, Shimasaki, Takafumi, Aiba, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214231/
https://www.ncbi.nlm.nih.gov/pubmed/35765188
http://dx.doi.org/10.1002/mbo3.1303
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author Ohtsuka, Hokuto
Imada, Kazuki
Shimasaki, Takafumi
Aiba, Hirofumi
author_facet Ohtsuka, Hokuto
Imada, Kazuki
Shimasaki, Takafumi
Aiba, Hirofumi
author_sort Ohtsuka, Hokuto
collection PubMed
description The fission yeast Schizosaccharomyces pombe employs two main strategies to adapt to the environment and survive when starved for nutrients. The strategies employ sporulation via sexual differentiation and extension of the chronological lifespan. When a cell is exposed to nutrient starvation in the presence of a cell of the opposite sex, the cells undergo fusion through conjugation and sporulation through meiosis. S. pombe spores are highly resistant to diverse stresses and may survive for a very long time. In this minireview, among the various sexual differentiation processes induced by starvation, we focused on and summarized the findings of the molecular mechanisms of spore formation in fission yeast. Furthermore, comparative measurements of the chronological lifespan of stationary phase cells and G(0) cells and the survival period of spore cells revealed that the spore cells survived for a long period, indicating the presence of an effective mechanism for survival. Currently, many molecules involved in sporulation and their functions are being discovered; however, our understanding of these is not complete. Further understanding of spores may not only deepen our comprehension of sexual differentiation but may also provide hints for sustaining life.
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spelling pubmed-92142312022-06-29 Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombe Ohtsuka, Hokuto Imada, Kazuki Shimasaki, Takafumi Aiba, Hirofumi Microbiologyopen Reviews The fission yeast Schizosaccharomyces pombe employs two main strategies to adapt to the environment and survive when starved for nutrients. The strategies employ sporulation via sexual differentiation and extension of the chronological lifespan. When a cell is exposed to nutrient starvation in the presence of a cell of the opposite sex, the cells undergo fusion through conjugation and sporulation through meiosis. S. pombe spores are highly resistant to diverse stresses and may survive for a very long time. In this minireview, among the various sexual differentiation processes induced by starvation, we focused on and summarized the findings of the molecular mechanisms of spore formation in fission yeast. Furthermore, comparative measurements of the chronological lifespan of stationary phase cells and G(0) cells and the survival period of spore cells revealed that the spore cells survived for a long period, indicating the presence of an effective mechanism for survival. Currently, many molecules involved in sporulation and their functions are being discovered; however, our understanding of these is not complete. Further understanding of spores may not only deepen our comprehension of sexual differentiation but may also provide hints for sustaining life. John Wiley and Sons Inc. 2022-06-21 /pmc/articles/PMC9214231/ /pubmed/35765188 http://dx.doi.org/10.1002/mbo3.1303 Text en © 2022 The Authors. MicrobiologyOpen published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Ohtsuka, Hokuto
Imada, Kazuki
Shimasaki, Takafumi
Aiba, Hirofumi
Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombe
title Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombe
title_full Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombe
title_fullStr Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombe
title_full_unstemmed Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombe
title_short Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombe
title_sort sporulation: a response to starvation in the fission yeast schizosaccharomyces pombe
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214231/
https://www.ncbi.nlm.nih.gov/pubmed/35765188
http://dx.doi.org/10.1002/mbo3.1303
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