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Transcriptomic Analysis of Dysregulated Genes of the nDNA-mtDNA Axis in a Mouse Model of Dilated Cardiomyopathy

Background: Mitochondrial dysfunction is implicated in the development of cardiomyopathy and heart failure. Transcription of mitochondrial DNA (mtDNA) encoded genes and subsequent protein synthesis are tightly regulated by nuclear DNA (nDNA) encoded proteins forming the nDNA-mtDNA axis. The scale of...

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Detalles Bibliográficos
Autores principales:	Ziemann, Mark, Wu, Wei, Deng, Xiu-Ling, Du, Xiao-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214240/ https://www.ncbi.nlm.nih.gov/pubmed/35754828 http://dx.doi.org/10.3389/fgene.2022.921610

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