Early Feasibility Assessment: A Method for Accurately Predicting Biotherapeutic Dosing to Inform Early Drug Discovery Decisions

The application of model-informed drug discovery and development (MID3) approaches in the early stages of drug discovery can help determine feasibility of drugging a target, prioritize between targets, or define optimal drug properties for a target product profile (TPP). However, applying MID3 in ea...

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Detalles Bibliográficos
Autores principales: Marcantonio, Diana H., Matteson, Andrew, Presler, Marc, Burke, John M., Hagen, David R., Hua, Fei, Apgar, Joshua F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214263/
https://www.ncbi.nlm.nih.gov/pubmed/35754500
http://dx.doi.org/10.3389/fphar.2022.864768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214263/
https://www.ncbi.nlm.nih.gov/pubmed/35754500
http://dx.doi.org/10.3389/fphar.2022.864768

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