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Early Feasibility Assessment: A Method for Accurately Predicting Biotherapeutic Dosing to Inform Early Drug Discovery Decisions
The application of model-informed drug discovery and development (MID3) approaches in the early stages of drug discovery can help determine feasibility of drugging a target, prioritize between targets, or define optimal drug properties for a target product profile (TPP). However, applying MID3 in ea...
Autores principales: | Marcantonio, Diana H., Matteson, Andrew, Presler, Marc, Burke, John M., Hagen, David R., Hua, Fei, Apgar, Joshua F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214263/ https://www.ncbi.nlm.nih.gov/pubmed/35754500 http://dx.doi.org/10.3389/fphar.2022.864768 |
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