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Intrinsic neural stem cell properties define brain hypersensitivity to genotoxic stress

Impaired replication has been previously linked to growth retardation and microcephaly; however, why the brain is critically affected compared with other organs remains elusive. Here, we report the differential response between early neural progenitors (neuroepithelial cells [NECs]) and fate-committ...

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Detalles Bibliográficos
Autores principales: Kalogeropoulou, Argyro, Mougkogianni, Maria, Iliadou, Marianna, Nikolopoulou, Eleni, Flordelis, Stefanos, Kanellou, Alexandra, Arbi, Marina, Nikou, Sofia, Nieminuszczy, Jadwiga, Niedzwiedz, Wojciech, Kardamakis, Dimitrios, Bravou, Vasiliki, Lygerou, Zoi, Taraviras, Stavros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214316/
https://www.ncbi.nlm.nih.gov/pubmed/35623353
http://dx.doi.org/10.1016/j.stemcr.2022.04.018

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