Prediction of lipid nanoparticles for mRNA vaccines by the machine learning algorithm

Lipid nanoparticle (LNP) is commonly used to deliver mRNA vaccines. Currently, LNP optimization primarily relies on screening ionizable lipids by traditional experiments which consumes intensive cost and time. Current study attempts to apply computational methods to accelerate the LNP development fo...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Feng, Shuo, Ye, Zhuyifan, Gao, Hanlu, Lin, Jinzhong, Ouyang, Defang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214321/
https://www.ncbi.nlm.nih.gov/pubmed/35755271
http://dx.doi.org/10.1016/j.apsb.2021.11.021

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