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Alpha-2-adrenergic receptor agonists for the prevention of delirium and cognitive decline after open heart surgery (ALPHA2PREVENT): protocol for a multicentre randomised controlled trial

INTRODUCTION: Postoperative delirium is common in older cardiac surgery patients and associated with negative short-term and long-term outcomes. The alpha-2-adrenergic receptor agonist dexmedetomidine shows promise as prophylaxis and treatment for delirium in intensive care units (ICU) and postopera...

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Detalles Bibliográficos
Autores principales:	Neerland, Bjørn Erik, Busund, Rolf, Haaverstad, Rune, Helbostad, Jorunn L, Landsverk, Svein Aslak, Martinaityte, Ieva, Norum, Hilde Margrethe, Ræder, Johan, Selbaek, Geir, Simpson, Melanie R, Skaar, Elisabeth, Skjærvold, Nils Kristian, Skovlund, Eva, Slooter, Arjen JC, Svendsen, Øyvind Sverre, Tønnessen, Theis, Wahba, Alexander, Zetterberg, Henrik, Wyller, Torgeir Bruun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Anaesthesia
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214392/ https://www.ncbi.nlm.nih.gov/pubmed/35725264 http://dx.doi.org/10.1136/bmjopen-2021-057460

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