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Hypoxia-inducible lentiviral gene expression in engineered human macrophages

BACKGROUND: Human immune cells, including monocyte-derived macrophages, can be engineered to deliver proinflammatory cytokines, bispecific antibodies, and chimeric antigen receptors to support immune responses in different disease settings. When gene expression is regulated by constitutively active...

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Detalles Bibliográficos
Autores principales:	Chinn, Harrison K, Gardell, Jennifer L, Matsumoto, Lisa R, Labadie, Kevin P, Mihailovic, Tara N, Lieberman, Nicole A P, Davis, Amira, Pillarisetty, Venu G, Crane, Courtney A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214393/ https://www.ncbi.nlm.nih.gov/pubmed/35728871 http://dx.doi.org/10.1136/jitc-2021-003770

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