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Measuring thermodynamic preferences to form non-native conformations in nucleic acids using ultraviolet melting
Thermodynamic preferences to form non-native conformations are crucial for understanding how nucleic acids fold and function. However, they are difficult to measure experimentally because this requires accurately determining the population of minor low-abundance (<10%) conformations in a sea of o...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214542/ https://www.ncbi.nlm.nih.gov/pubmed/35671421 http://dx.doi.org/10.1073/pnas.2112496119 |