Cargando…

Induction of M-MDSCs with IL6/GM-CSF from adherence monocytes and inhibition by WP1066

Peripheral blood monocytes acquire the phenotype of myeloid-derived suppressor cells (MDSCs) by induction of cytokine or co-culture with cancer cells and are widely used to model MDSCs for in vitro studies. However, the simplest method of plastic adhesive sorting is poorly described as the purity of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Hao, Xiang, Yuan, Li, Ting, Yu, Qi-Ying, Gu, Li-Xing, Liao, Xing-Hua, Zhang, Tong-Cun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214597/ https://www.ncbi.nlm.nih.gov/pubmed/35761803 http://dx.doi.org/10.3892/etm.2022.11414

Ejemplares similares

Glutamine Deprivation Promotes the Generation and Mobilization of MDSCs by Enhancing Expression of G-CSF and GM-CSF
por: Sun, Hong-Wei, et al.
Publicado: (2021)

MDSCs are involved in the protumorigenic potentials of GM-CSF in colitis-associated cancer
por: Ma, Ning, et al.
Publicado: (2017)

STAT3 inhibitor WP1066 as a novel therapeutic agent for renal cell carcinoma
por: Horiguchi, A, et al.
Publicado: (2010)

WP1066 induces cell death in a schwannomatosis patient–derived schwannoma cell line
por: Allaf, Abdulrahman, et al.
Publicado: (2022)

GM-CSF-mediated inducement of bone marrow MDSCs by TSA and effect on survival of graft in mice
por: Zhao, Shuguang, et al.
Publicado: (2022)

WP1066 suppresses macrophage cell death induced by inflammasome agonists independently of its inhibitory effect on STAT3
por: Honda, Shino, et al.
Publicado: (2017)

WP1066 Sensitizes Oral Squamous Cell Carcinoma Cells to Cisplatin by Targeting STAT3/miR-21 axis
por: Zhou, Xuan, et al.
Publicado: (2014)

A first-in-human Phase I trial of the oral p-STAT3 inhibitor WP1066 in patients with recurrent malignant glioma
por: de Groot, John, et al.
Publicado: (2022)

Functional characterization of GM-CSF induced monocyte subsets
por: Däbritz, J, et al.
Publicado: (2008)

IL-1β and TNFα Promote Monocyte Viability through the Induction of GM-CSF Expression by Rheumatoid Arthritis Synovial Fibroblasts
por: Darrieutort-Laffite, Christelle, et al.
Publicado: (2014)

GM-CSF Primes Proinflammatory Monocyte Responses in Ankylosing Spondylitis
por: Shi, Hui, et al.
Publicado: (2020)

IL-34 Induces the Differentiation of Human Monocytes into Immunosuppressive Macrophages. Antagonistic Effects of GM-CSF and IFNγ
por: Foucher, Etienne D., et al.
Publicado: (2013)

Neutrophil Extracellular Traps Reprogram IL-4/GM-CSF-Induced Monocyte Differentiation to Anti-inflammatory Macrophages
por: Guimarães-Costa, Anderson B., et al.
Publicado: (2017)

Evaluation of the effect of GM-CSF blocking on the phenotype and function of human monocytes
por: Lotfi, Noushin, et al.
Publicado: (2020)

Adhesion-independent synergy of monocytes and endothelial cells in cytokine production: regulation of IL-6 and GM–CSF production by PAF
por: Lacasse, C., et al.
Publicado: (1996)

Correction: IL-34 Induces the Differentiation of Human Monocytes into Immunosuppressive Macrophages. Antagonistic Effects of GM-CSF and IFNγ
por: Foucher, Etienne D., et al.
Publicado: (2014)

GM-CSF and IL-3 Modulate Human Monocyte TNF-α Production and Renewal in In Vitro Models of Trained Immunity
por: Borriello, Francesco, et al.
Publicado: (2017)

GM-CSF Signalling Boosts Dramatically IL-1Production
por: Khameneh, Hanif Javanmard, et al.
Publicado: (2011)

Utility of monocyte HLA-DR and rationale for therapeutic GM-CSF in sepsis immunoparalysis
por: Joshi, Ila, et al.
Publicado: (2023)

GM-CSF in inflammation
por: Hamilton, John A.
Publicado: (2019)

Irradiated Bladder Cancer Cells Expressing both GM-CSF and IL-21 versus Either GM-CSF or IL-21 Alone as Tumor Vaccine in a Mouse Xenograft Model
por: Peng, Junming, et al.
Publicado: (2019)

1066 Delay in the Norwegian Immunisation Programme
por: Riise, Oystein
Publicado: (2014)

IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression
por: Casella, Giacomo, et al.
Publicado: (2017)

Innate Immune Modulation by GM-CSF and IL-3 in Health and Disease
por: Borriello, Francesco, et al.
Publicado: (2019)

Stroke-Induced Modulation of Myeloid-Derived Suppressor Cells (MDSCs) and IL-10-Producing Regulatory Monocytes
por: Achmus, Lennart, et al.
Publicado: (2020)

G-CSF and GM-CSF in clinical trials.
por: Antman, K. H.
Publicado: (1990)

GM-CSF Monocyte-Derived Cells and Langerhans Cells As Part of the Dendritic Cell Family
por: Lutz, Manfred B., et al.
Publicado: (2017)

Recombinant GM-CSF for diseases of GM-CSF insufficiency: Correcting dysfunctional mononuclear phagocyte disorders
por: Lazarus, Hillard M., et al.
Publicado: (2023)

Development of Membrane-Bound GM-CSF and IL-18 as an Effective Tumor Vaccine
por: Huang, Chien-Chiao, et al.
Publicado: (2015)

HIV Replication in Humanized IL-3/GM-CSF-Transgenic NOG Mice
por: Perdomo-Celis, Federico, et al.
Publicado: (2019)

Closing Symposium of the DFG Research Unit FOR 1066
por: Radespiel, Rolf, et al.
Publicado: (2016)

The four orchestral suites, BWV 1066-1069 /
por: Bach, Johann Sebastian, 1685-1750
Publicado: (2000)

Research Upregulation of CD23 (FcεRII) Expression in Human Airway Smooth Muscle Cells (huASMC) in Response to IL-4, GM-CSF, and IL-4/GM-CSF
por: Belleau, Joseph T, et al.
Publicado: (2005)

GM-CSF Quantity Has a Selective Effect on Granulocytic vs. Monocytic Myeloid Development and Function
por: Sun, Li, et al.
Publicado: (2018)

Systemic Monocytic-MDSCs Are Generated from Monocytes and Correlate with Disease Progression in Breast Cancer Patients
por: Bergenfelz, Caroline, et al.
Publicado: (2015)

4 Ouvertüren, BWV 1066-1069 Suites ; Ouvertüre BWV 1070 /
por: Bach, Johann Sebastian, 1685-1750
Publicado: (1986)

Clinical relevance of systemic monocytic-MDSCs in patients with metastatic breast cancer
por: Bergenfelz, Caroline, et al.
Publicado: (2020)

Requirements and constraints of arc design options on WP3, WP4, WP5: Deliverable D2.3
por: Chance, Antoine
Publicado: (2017)

Requirements and constraints of EIR design option on WP2, WP4, WP5: Milestone M3.3
por: Seryi, Andrei
Publicado: (2017)

Role of GM-CSF in lung balance and disease
por: Chen, Yingzi, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_vkuqr3u4m3iq8dbmb63bd6vjs1