Cargando…

In vitro and in silico studies of SARS-CoV-2 main protease M(pro) inhibitors isolated from Helichrysum bracteatum

Discovering SARS-CoV-2 inhibitors from natural sources is still a target that has captured the interest of many researchers. In this study, the compounds (1–18) present in the methanolic extract of Helichrysum bracteatum were isolated, identified, and their in vitro inhibitory activities against SAR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wahab, Gehad Abdel, Aboelmaaty, Walaa S., Lahloub, Mohamed Farid, Sallam, Amal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214608/ https://www.ncbi.nlm.nih.gov/pubmed/35799933 http://dx.doi.org/10.1039/d2ra01213h

Ejemplares similares

Protease-inhibiting, molecular modeling and antimicrobial activities of extracts and constituents from Helichrysum foetidum and Helichrysum mechowianum (compositae)
por: Malolo, Fanny-Aimée Essombe, et al.
Publicado: (2015)

In silico approach for identification of natural compounds as potential COVID 19 main protease (M(pro)) inhibitors
por: Chaturvedi, Monika, et al.
Publicado: (2021)

In Silico Mining of Terpenes from Red-Sea Invertebrates for SARS-CoV-2 Main Protease (M(pro)) Inhibitors
por: Ibrahim, Mahmoud A. A., et al.
Publicado: (2021)

In silico investigation of saponins and tannins as potential inhibitors of SARS-CoV-2 main protease (M(pro))
por: Falade, Victoria Adeola, et al.
Publicado: (2021)

Neuroprotective effects of a Coeloglossum viride var. Bracteatum extract in vitro and in vivo
por: Pan, Rui-Yuan, et al.
Publicado: (2017)

A Comparative Study of the Antioxidative Effects of Helichrysum italicum and Helichrysum arenarium Infusions
por: Kramberger, Katja, et al.
Publicado: (2021)

Diphenyl Diselenide and SARS-CoV-2: in silico Exploration of the Mechanisms of Inhibition of Main Protease (M(pro)) and Papain-like Protease (PL(pro))
por: Omage, Folorunsho Bright, et al.
Publicado: (2023)

An in-silico investigation of potential natural polyphenols for the targeting of COVID main protease inhibitor
por: Aljarba, Nada H., et al.
Publicado: (2022)

In silico assessment of diterpenes as potential inhibitors of SARS-COV-2 main protease
por: Abdelrady, Yousef A, et al.
Publicado: (2023)

In silico analysis of selected alkaloids against main protease (M(pro)) of SARS-CoV-2
por: Garg, Saksham, et al.
Publicado: (2020)

Novel Anti-Aging Benzoquinone Derivatives from Onosma bracteatum Wall
por: Farooq, Umer, et al.
Publicado: (2019)

Abietane Diterpenoids Isolated from Clerodendrum bracteatum and Their Antioxidant and Cytotoxic Activities
por: Li, Pingting, et al.
Publicado: (2021)

An in-silico evaluation of COVID-19 main protease with clinically approved drugs
por: Tachoua, Wafa, et al.
Publicado: (2020)

In silico analysis of echinocandins binding to the main proteases of coronaviruses PEDV (3CL(pro)) and SARS-CoV-2 (M(pro))
por: Vergoten, Gérard, et al.
Publicado: (2021)

Araucaria heterophylla oleogum resin essential oil is a novel aldose reductase and butyryl choline esterase enzymes inhibitor: in vitro and in silico evidence
por: Soliman, Amal F., et al.
Publicado: (2023)

In Silico Evaluation of the Effectivity of Approved Protease Inhibitors against the Main Protease of the Novel SARS-CoV-2 Virus
por: Eleftheriou, Phaedra, et al.
Publicado: (2020)

In Silico and In Vitro Identification of Pan-Coronaviral Main Protease Inhibitors from a Large Natural Product Library
por: Shahhamzehei, Nasim, et al.
Publicado: (2022)

In silico drug discovery of major metabolites from spices as SARS-CoV-2 main protease inhibitors
por: Ibrahim, Mahmoud A.A., et al.
Publicado: (2020)

Hordatines as a Potential Inhibitor of COVID-19 Main Protease and RNA Polymerase: An In-Silico Approach
por: Dahab, Mohammed A., et al.
Publicado: (2020)

Recognition of Natural Products as Potential Inhibitors of COVID-19 Main Protease (Mpro): In-Silico Evidences
por: Narkhede, Rohan R., et al.
Publicado: (2020)

2-Phenoxyacetamide derivatives as SARS-CoV-2 main protease inhibitor: In silico studies
por: Hariyono, Pandu, et al.
Publicado: (2022)

Apigenin analogues as SARS-CoV-2 main protease inhibitors: In-silico screening approach
por: Farhat, Ameny, et al.
Publicado: (2022)

In silico structure-based discovery of a SARS-CoV-2 main protease inhibitor
por: Wen, Lei, et al.
Publicado: (2021)

Screening, molecular simulation & in silico kinetics of virtually designed covid-19 main protease inhibitors
por: Aleissa, Mohammed S., et al.
Publicado: (2022)

In Silico Discovery of Small-Molecule Inhibitors Targeting SARS-CoV-2 Main Protease
por: Gao, Menghan, et al.
Publicado: (2023)

Rapid identification of a narcotic plant Papaver bracteatum using flow cytometry
por: Aragane, Masako, et al.
Publicado: (2014)

In Silico Substrate-Binding Profiling for SARS-CoV-2 Main Protease (M(pro)) Using Hexapeptide Substrates
por: Zabo, Sophakama, et al.
Publicado: (2023)

Repurposing of US-FDA approved drugs against SARS-CoV-2 main protease (M(pro)) by using STD-NMR spectroscopy, in silico studies and antiviral assays
por: Khan, Abdul Mateen, et al.
Publicado: (2023)

Synthesis of New Binary Thiazole-Based Heterocycles and Their Molecular Docking Study as COVID-19 Main Protease (M(pro)) Inhibitors
por: Abdel-Latif, E., et al.
Publicado: (2021)

Review on development of potential inhibitors of SARS-CoV-2 main protease (M(Pro))
por: Katre, Soumya Gulab, et al.
Publicado: (2022)

In-silico screening of naturally derived phytochemicals against SARS-CoV Main protease
por: Mostafa, Islam, et al.
Publicado: (2021)

Rutin and flavone analogs as prospective SARS-CoV-2 main protease inhibitors: In silico drug discovery study
por: Ibrahim, Mahmoud A.A., et al.
Publicado: (2021)

In silico study of medicinal plants with cyclodextrin inclusion complex as the potential inhibitors against SARS-CoV-2 main protease (M(pro)) and spike (S) receptor
por: Dermawan, Doni, et al.
Publicado: (2021)

HPLC Analysis and In Vitro and In Silico Evaluation of the Biological Activity of Polyphenolic Components Separated with Solvents of Various Polarities from Helichrysum italicum
por: Bojilov, Dimitar, et al.
Publicado: (2023)

In silico fight against novel coronavirus by finding chromone derivatives as inhibitor of coronavirus main proteases enzyme
por: Sepay, Nayim, et al.
Publicado: (2020)

In Silico Study of Coumarins and Quinolines Derivatives as Potent Inhibitors of SARS-CoV-2 Main Protease
por: Yañez, Osvaldo, et al.
Publicado: (2021)

In silico investigation of potential inhibitors to main protease and spike protein of SARS-CoV-2 in propolis
por: Harisna, Azza Hanif, et al.
Publicado: (2021)

In silico discovery of SARS-CoV-2 main protease inhibitors from the carboline and quinoline database
por: Muhtar, Eldar, et al.
Publicado: (2021)

In silico Screening of Potential SARS-CoV-2 Main Protease Inhibitors from Thymus schimperi
por: Mengist, Hylemariam Mihiretie, et al.
Publicado: (2023)

Antioxidant and Toxic Activity of Helichrysum arenarium (L.) Moench and Helichrysum italicum (Roth) G. Don Essential Oils and Extracts
por: Judzentiene, Asta, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_300rhc68n1p948s32fbmrbas2a