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The parasite cytokine mimic Hp‐TGM potently replicates the regulatory effects of TGF‐β on murine CD4(+) T cells

Transforming growth factor‐beta (TGF‐β) family proteins mediate many vital biological functions in growth, development and regulation of the immune system. TGF‐β itself controls immune homeostasis and inflammation, including conversion of naïve CD4(+) T cells into Foxp3(+) regulatory T cells (Tregs)...

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Detalles Bibliográficos
Autores principales: White, Madeleine P J, Smyth, Danielle J, Cook, Laura, Ziegler, Steven F, Levings, Megan K, Maizels, Rick M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214624/
https://www.ncbi.nlm.nih.gov/pubmed/33988885
http://dx.doi.org/10.1111/imcb.12479